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    mrpl18 mitochondrial ribosomal protein L18 [ Danio rerio (zebrafish) ]

    Gene ID: 768187, updated on 2-Nov-2024

    Summary

    Official Symbol
    mrpl18provided by ZNC
    Official Full Name
    mitochondrial ribosomal protein L18provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-632
    See related
    Ensembl:ENSDARG00000060199 AllianceGenome:ZFIN:ZDB-GENE-061013-632
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153420
    Summary
    Predicted to enable 5S rRNA binding activity. Predicted to act upstream of or within translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human MRPL18 (mitochondrial ribosomal protein L18). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See mrpl18 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (35499678..35505494, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (35159364..35165207, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene si:ch211-203d1.3 Neighboring gene sushi-repeat containing protein X-linked 2 Neighboring gene platelet derived growth factor c Neighboring gene glycine receptor, beta b Neighboring gene glutamate receptor, ionotropic, AMPA 2b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 5S rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein uL18m

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077330.1NP_001070798.1  large ribosomal subunit protein uL18m

      See identical proteins and their annotated locations for NP_001070798.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124672
      UniProtKB/TrEMBL
      Q08BK7
      Related
      ENSDARP00000079005.5, ENSDART00000084570.6
      Conserved Domains (1) summary
      cd00432
      Location:78181
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      35499678..35505494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157321.4XP_005157378.1  large ribosomal subunit protein uL18m isoform X1

      UniProtKB/TrEMBL
      A0A8M2B437, E9QDQ8
      Related
      ENSDARP00000117764.1, ENSDART00000133658.3
      Conserved Domains (1) summary
      cd00432
      Location:77180
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394920.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      35356..41125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395318.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      36134..41932 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)