lima1a LIM domain and actin binding 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lima1aprovided by ZNC
Official Full Name: LIM domain and actin binding 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-001120-1
See related: Ensembl:ENSDARG00000101441 AllianceGenome:ZFIN:ZDB-GENE-001120-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eplin; lima1; cb1006; wu:fd15g06; wu:fd20b10
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be active in actin cytoskeleton and plasma membrane. Is expressed in several structures, including blood vessel; hindbrain neural plate; midbrain neural keel; nervous system; and periderm. Orthologous to human LIMA1 (LIM domain and actin binding 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (36450916..36488629)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (36354198..36365453)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in actin filament bundle assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: LIM domain and actin-binding protein 1a

Names: LIM domain and actin binding 1; cytoskeleton-associated LIM domain protein; epithelial protein lost in neoplasm

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131664.1 → NP_571739.1 LIM domain and actin-binding protein 1a

See identical proteins and their annotated locations for NP_571739.1

Status: PROVISIONAL

Source sequence(s)

AF307846

UniProtKB/TrEMBL

Q9DEY8

Related

ENSDARP00000132530.2, ENSDART00000172441.2

Conserved Domains (1) summary

cd09485
Location:286 → 338

LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)