oip5-as1 oip5 antisense RNA 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: oip5-as1provided by ZNC
Official Full Name: oip5 antisense RNA 1provided by ZNC
Primary source: ZFIN:ZDB-LINCRNAG-030131-2500
See related: Ensembl:ENSDARG00000093456 AllianceGenome:ZFIN:ZDB-LINCRNAG-030131-2500
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc10a02; linc-oip5; wu:fc10a02; si:dkey-71p21.9
Summary: Predicted to enable miRNA binding activity. Is expressed in several structures, including heart; integument; notochord; pleuroperitoneal region; and unfertilized egg. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human OIP5-AS1 (OIP5 antisense RNA 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (33261131..33267584, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (33130681..33137134, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In the inherited pool, we noticed a conserved lncRNA, Cyrano previously known for zebrafish brain development. Knockdown of inherited Cyrano by miR-7 without changing zygotic Cyrano altered brain morphology at 24 hpf and 48 hpf.
Title: Parentally inherited long non-coding RNA Cyrano is involved in zebrafish neurodevelopment.
Perturbation of this lincRNA causes small heads and eyes, short, curly tails, defects in neural tube opening, loss of NeuroD-positive neurons in the retina and tectum, and enlarged nasal placodes. We named this lincRNA cyrano.
Title: Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution.

Submit: New GeneRIF Correction

General gene information

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Markers

fc10a02.x1 (e-PCR)
- UniSTS:192415

fc10a02.x1 (e-PCR)
- UniSTS:192416

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables miRNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.