sh3bp5b SH3-domain binding protein 5b (BTK-associated) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sh3bp5bprovided by ZNC
Official Full Name: SH3-domain binding protein 5b (BTK-associated)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2813
See related: Ensembl:ENSDARG00000103978 AllianceGenome:ZFIN:ZDB-GENE-040426-2813
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sh3bp5; zgc:55565; wu:fj55c06
Summary: Predicted to enable protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in intermediate cell mass of mesoderm and male organism. Orthologous to human SH3BP5 (SH3 domain binding protein 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (36126973..36163267)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (36118324..36154618)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables SH3 domain binding	IEA Inferred from Electronic Annotation more info
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
enables protein kinase inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SH3 domain-binding protein 5b

Names: SH3-domain binding protein 5 (BTK-associated)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.