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    sqor sulfide quinone oxidoreductase [ Danio rerio (zebrafish) ]

    Gene ID: 550580, updated on 2-Nov-2024

    Summary

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    Official Symbol
    sqorprovided by ZNC
    Official Full Name
    sulfide quinone oxidoreductaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-436
    See related
    Ensembl:ENSDARG00000017034 AllianceGenome:ZFIN:ZDB-GENE-050417-436
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sqrdl; fj81h04; wu:fj81h04; zgc:113156
    Summary
    Predicted to enable FAD binding activity and sulfide:quinone oxidoreductase activity. Predicted to be involved in sulfide oxidation, using sulfide:quinone oxidoreductase. Predicted to be active in mitochondrion. Orthologous to human SQOR (sulfide quinone oxidoreductase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See sqor in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (32473437..32495363)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (32062267..32084406)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene galactokinase 2 Neighboring gene ATPase phospholipid transporting 8B4 Neighboring gene CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a Neighboring gene S-phase cyclin A-associated protein in the ER

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Thermal stress induces a positive phenotypic and molecular feedback loop in zebrafish embryos. Feugere L, et al. J Therm Biol, 2021 Dec. PMID 34863478
    2. Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans. Driessen M, et al. Toxicol Lett, 2014 Oct 1. PMID 25064622
    3. Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression. Henry TB, et al. Environ Health Perspect, 2007 Jul. PMID 17637923, Free PMC Article
    4. An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex. Zhang P, et al. Elife, 2016 Jan 14. PMID 26765566, Free PMC Article
    5. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Zhang P, et al. Cell Rep, 2014 Mar 27. PMID 24613356

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables FAD binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sulfide:quinone oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in sulfide oxidation, using sulfide:quinone oxidoreductase IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sulfide:quinone oxidoreductase, mitochondrial
    Names
    sulfide quinone reductase-like
    NP_001017881.1
    XP_021326165.1
    XP_068073472.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017881.1 → NP_001017881.1  sulfide:quinone oxidoreductase, mitochondrial

      See identical proteins and their annotated locations for NP_001017881.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093431
      UniProtKB/TrEMBL
      Q566N7
      Related
      ENSDARP00000117779.1, ENSDART00000146451.3
      Conserved Domains (1) summary
      COG0446
      Location:40 → 380
      FadH2; NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      32473437..32495363
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217371.1 → XP_068073472.1  sulfide:quinone oxidoreductase, mitochondrial isoform X1

    2. XM_021470490.2 → XP_021326165.1  sulfide:quinone oxidoreductase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8M9PYD6
      Conserved Domains (1) summary
      COG0446
      Location:40 → 380
      FadH2; NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism]
    Nucleotide Protein Strain
    Heading Accession and Version

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