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    Tmem223 transmembrane protein 223 [ Mus musculus (house mouse) ]

    Gene ID: 66836, updated on 28-Oct-2024

    Summary

    Official Symbol
    Tmem223provided by MGI
    Official Full Name
    transmembrane protein 223provided by MGI
    Primary source
    MGI:MGI:1914086
    See related
    Ensembl:ENSMUSG00000117924 AllianceGenome:MGI:1914086
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610006I08Rik
    Summary
    Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Is expressed in embryo. Orthologous to human TMEM223 (transmembrane protein 223). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 132.8), ovary adult (RPKM 100.2) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Tmem223 in Genome Data Viewer
    Location:
    19 A; 19 5.54 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8748360..8749839)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8770996..8772475)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene syntaxin 5A Neighboring gene RIKEN cDNA 1700023D09 gene Neighboring gene STARR-seq mESC enhancer starr_45493 Neighboring gene nuclear RNA export factor 1 Neighboring gene transmembrane protein 179B Neighboring gene interferon induced transmembrane protein 2 pseudogene Neighboring gene TATA-box binding protein associated factor 6 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mitochondrial ribosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial cytochrome c oxidase assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025791.1NP_080067.1  transmembrane protein 223

      See identical proteins and their annotated locations for NP_080067.1

      Status: VALIDATED

      Source sequence(s)
      AK002249
      Consensus CDS
      CCDS29544.1
      UniProtKB/Swiss-Prot
      Q9CQE2
      Related
      ENSMUSP00000010248.4, ENSMUST00000010248.4
      Conserved Domains (1) summary
      pfam14640
      Location:32197
      TMEM223; Transmembrane protein 223

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      8748360..8749839
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)