U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CDR1 cerebellar degeneration related 1 [ Homo sapiens (human) ]

    Gene ID: 1038, updated on 8-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CDR1provided by HGNC
    Official Full Name
    cerebellar degeneration related 1provided by HGNC
    Primary source
    HGNC:HGNC:1798
    See related
    MIM:302650; AllianceGenome:HGNC:1798
    Gene type
    unknown
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CDR; CDR34; CDR62A
    Orthologs
    all

    Genomic context

    Go to the top of the page Help
    See CDR1 in Genome Data Viewer
    Location:
    Xq27.1
    Annotation release Status Assembly Chr Location
    RS_2023_10 latest, but not current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (140772083..140793212, complement)
    RS_2023_10 latest, but not current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (139089454..139110579, complement)

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis. Wang LL, et al. Curr Med Sci, 2020 Jun. PMID 32681261
    2. Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease. Bosco P, et al. Neurol Sci, 2014 Oct. PMID 24777548
    3. Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in prostate cancer cell lines. Salemi M, et al. Int J Biol Markers, 2014 Sep 30. PMID 24366849
    4. The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus. Sthoeger Z, et al. PLoS One, 2013. PMID 23555966, Free PMC Article
    5. Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration. Dropcho EJ, et al. Proc Natl Acad Sci U S A, 1987 Jul. PMID 3474619, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
      Title: Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
    2. Underexpression of CDR1 is associated with glioblastoma multiforme.
      Title: Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.
    3. The results of this case-control study showed that the CDR1 gene was over-expressed in five out of seven subjects with AD compared to seven age- and sex-matched normal controls. Data suggest that CDR1 gene may play a role, in Alzheimer's disease process.
      Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease.
    4. The CDR1 gene was overexpressed in the LNCaP and PC-3 PCa cell lines as compared with the PNT1A normal prostate cell line.
      Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in prostate cancer cell lines.
    5. Treatment of systemic lupus erythematosus afflicted (NZBxNZW)F1 mice with human CDR1 down regulated gene expression of IFN-alpha.
      Title: The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus.
    6. miR-671 directs cleavage of a circular antisense transcript of the Cerebellar Degeneration-Related protein 1 (CDR1) locus in an Ago2-slicer-dependent manner.
      Title: miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA.
    Submit: New GeneRIF Correction

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Other Names

    • cerebellar degeneration related protein 1
    • cerebellar degeneration-related antigen 1
    • cerebellar degeneration-related protein 1, 34kDa

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_016361.1: Suppressed sequence

      Description
      NG_016361.1: This RefSeq was removed by NCBI staff.

    2. NM_004065.2: Suppressed sequence

      Description
      NM_004065.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P51861.2 GenPept UniProtKB/Swiss-Prot:P51861

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools