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    SPG5 Spg5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855229, updated on 1-Aug-2024

    Summary

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    Gene symbol
    SPG5
    Gene description
    Spg5p
    Primary source
    FungiDB:YMR191W
    Locus tag
    YMR191W
    See related
    SGD:S000004803; AllianceGenome:SGD:S000004803; VEuPathDB:YMR191W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables proteasome binding activity. Involved in proteasome assembly. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SPG5 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (645656..646777)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene glycine decarboxylase subunit P Neighboring gene ATP-dependent DNA helicase SGS1 Neighboring gene Gyl1p Neighboring gene mitochondrial 54S ribosomal protein YmL24/YmL14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spg5 protein regulates the proteasome in quiescence. Hanna J, et al. J Biol Chem, 2012 Oct 5. PMID 22904326, Free PMC Article
    2. Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Martinez MJ, et al. Mol Biol Cell, 2004 Dec. PMID 15456898, Free PMC Article
    3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
    4. Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated. Voynova NS, et al. Eukaryot Cell, 2015 Dec. PMID 26432633, Free PMC Article
    5. Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Gallina I, et al. Nat Commun, 2015 Mar 30. PMID 25817432, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables proteasome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables proteasome binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteasome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Spg5p
    NP_013916.2
    • Protein required for proteasome assembly during quiescence; binds to base of the proteasome regulartory particle; required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      645656..646777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182697.1 → NP_013916.2  TPA: Spg5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013916.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W015, P42933
      UniProtKB/TrEMBL
      C8ZF55, N1P0H2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42933.3

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