U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Gpaa1 glycosylphosphatidylinositol anchor attachment 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300046, updated on 14-Nov-2024

    Summary

    Official Symbol
    Gpaa1provided by RGD
    Official Full Name
    glycosylphosphatidylinositol anchor attachment 1provided by RGD
    Primary source
    RGD:1303197
    See related
    EnsemblRapid:ENSRNOG00000029280 AllianceGenome:RGD:1303197
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GPI-anchor transamidase activity. Predicted to contribute to GPI anchor binding activity. Predicted to be involved in attachment of GPI anchor to protein and protein-containing complex assembly. Predicted to be located in several cellular components, including centrosome; endoplasmic reticulum; and mitochondrion. Predicted to be part of GPI-anchor transamidase complex. Orthologous to human GPAA1 (glycosylphosphatidylinositol anchor attachment 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 141.0), Thymus (RPKM 121.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gpaa1 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109932556..109936139)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108051896..108055479)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117394367..117397950)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene sphingomyelin phosphodiesterase 5 Neighboring gene 5-oxoprolinase (ATP-hydrolysing) Neighboring gene exosome component 4 Neighboring gene cytochrome c-1 Neighboring gene SHANK-associated RH domain interactor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC93877

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to GPI anchor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GPI-anchor transamidase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in attachment of GPI anchor to protein IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in attachment of GPI anchor to protein ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of GPI-anchor transamidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of GPI-anchor transamidase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of GPI-anchor transamidase complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycosylphosphatidylinositol anchor attachment 1 protein
    Names
    GPI anchor attachment protein 1
    anchor attachment protein 1
    glycosylphosphatidylinositol anchor attachment protein 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004240.1NP_001004240.1  glycosylphosphatidylinositol anchor attachment 1 protein

      See identical proteins and their annotated locations for NP_001004240.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078984
      UniProtKB/TrEMBL
      F7EVW7, Q6AYM8
      Related
      ENSRNOP00000050220.4, ENSRNOT00000048706.5
      Conserved Domains (1) summary
      pfam04114
      Location:126615
      Gaa1; Gaa1-like, GPI transamidase component

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      109932556..109936139
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)