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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_033898.2 RefSeqGene
- Range
-
5002..64070
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001270449.2 → NP_001257378.1 ubiquitin-protein ligase E3B isoform 3
See identical proteins and their annotated locations for NP_001257378.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate 3' exon, compared to variant 1. This difference results in a distinct 3' UTR and 3' coding region and a protein (isoform 3) with a shorter and distinct C-terminus, compared to isoform 1. Variants 4-6 encode the same protein (isoform 3).
- Source sequence(s)
-
BC051266, DA771082
- Consensus CDS
-
CCDS58277.1
- UniProtKB/TrEMBL
-
F5H6D6
- Related
- ENSP00000342614.5, ENST00000340074.9
-
NM_001270450.2 → NP_001257379.1 ubiquitin-protein ligase E3B isoform 3
See identical proteins and their annotated locations for NP_001257379.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR and contains an alternate 3' exon, compared to variant 1. These differences result in a distinct 3' UTR and 3' coding region and a protein (isoform 3) with a shorter and distinct C-terminus, compared to isoform 1. Variants 4-6 encode the same protein (isoform 3).
- Source sequence(s)
-
BC108705, DA771082
- Consensus CDS
-
CCDS58277.1
- UniProtKB/TrEMBL
-
F5H6D6
- Related
- ENSP00000440585.1, ENST00000536398.5
- Conserved Domains (1) summary
-
- cl15479
Location:30 → 50
- IQ; IQ calmodulin-binding motif
-
NM_001270451.2 → NP_001257380.1 ubiquitin-protein ligase E3B isoform 3
See identical proteins and their annotated locations for NP_001257380.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) uses an alternate splice site in the 5' UTR and contains an alternate 3' exon, compared to variant 1. These differences result in a distinct 3' UTR and 3' coding region and a protein (isoform 3) with a shorter and distinct C-terminus, compared to isoform 1. Variants 4-6 encode the same protein (isoform 3).
- Source sequence(s)
-
BC068221, BC108705, DA771082
- Consensus CDS
-
CCDS58277.1
- UniProtKB/TrEMBL
-
F5H6D6
- Related
- ENSP00000443565.1, ENST00000540230.5
- Conserved Domains (1) summary
-
- cl15479
Location:30 → 50
- IQ; IQ calmodulin-binding motif
-
NM_130466.4 → NP_569733.2 ubiquitin-protein ligase E3B isoform 1
See identical proteins and their annotated locations for NP_569733.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript, and encodes the longer protein (isoform 1). Variants 1 and 3 encode the same protein (isoform 1).
- Source sequence(s)
-
AF251046, BC032301, BC144684, BQ889238, DA771082, DR760197
- Consensus CDS
-
CCDS9129.1
- UniProtKB/Swiss-Prot
- A5D8Z3, Q05BX9, Q659F7, Q7Z3V4, Q7Z7Q1, Q9BXZ4
- UniProtKB/TrEMBL
-
B9EK57
- Related
- ENSP00000340596.3, ENST00000342494.8
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1066
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
NM_183415.3 → NP_904324.1 ubiquitin-protein ligase E3B isoform 1
See identical proteins and their annotated locations for NP_904324.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 5' UTR, as compared to variant 1. Variants 1 and 3 encode the same protein (isoform 1).
- Source sequence(s)
-
AF251046, BC032301, BQ889238, DA771082, DR760197
- Consensus CDS
-
CCDS9129.1
- UniProtKB/Swiss-Prot
- A5D8Z3, Q05BX9, Q659F7, Q7Z3V4, Q7Z7Q1, Q9BXZ4
- UniProtKB/TrEMBL
-
B9EK57
- Related
- ENSP00000391529.2, ENST00000434735.6
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1066
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
109477634..109547829
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011538961.2 → XP_011537263.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1007
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
XM_047429852.1 → XP_047285808.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429851.1 → XP_047285807.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429853.1 → XP_047285809.1 ubiquitin-protein ligase E3B isoform X6
- UniProtKB/TrEMBL
-
B9EK57
- Related
- ENSP00000443131.1, ENST00000539599.5
-
XM_047429844.1 → XP_047285800.1 ubiquitin-protein ligase E3B isoform X2
- UniProtKB/TrEMBL
-
B9EK57
-
XM_006719681.4 → XP_006719744.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1004
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
XM_006719682.3 → XP_006719745.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1004
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
XM_047429847.1 → XP_047285803.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_005253987.3 → XP_005254044.1 ubiquitin-protein ligase E3B isoform X1
See identical proteins and their annotated locations for XP_005254044.1
- UniProtKB/Swiss-Prot
- A5D8Z3, Q05BX9, Q659F7, Q7Z3V4, Q7Z7Q1, Q9BXZ4
- UniProtKB/TrEMBL
-
B9EK57
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1066
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
XM_047429845.1 → XP_047285801.1 ubiquitin-protein ligase E3B isoform X2
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429846.1 → XP_047285802.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429849.1 → XP_047285805.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429848.1 → XP_047285804.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_047429850.1 → XP_047285806.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
-
XM_011538959.3 → XP_011537261.1 ubiquitin-protein ligase E3B isoform X1
See identical proteins and their annotated locations for XP_011537261.1
- UniProtKB/Swiss-Prot
- A5D8Z3, Q05BX9, Q659F7, Q7Z3V4, Q7Z7Q1, Q9BXZ4
- UniProtKB/TrEMBL
-
B9EK57
- Conserved Domains (1) summary
-
- cd00078
Location:682 → 1066
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
-
XM_047429854.1 → XP_047285810.1 ubiquitin-protein ligase E3B isoform X7
-
XM_017020196.2 → XP_016875685.1 ubiquitin-protein ligase E3B isoform X8
- UniProtKB/TrEMBL
-
F5H6D6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
109452543..109519796
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054373776.1 → XP_054229751.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373778.1 → XP_054229753.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373777.1 → XP_054229752.1 ubiquitin-protein ligase E3B isoform X5
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373779.1 → XP_054229754.1 ubiquitin-protein ligase E3B isoform X6
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373767.1 → XP_054229742.1 ubiquitin-protein ligase E3B isoform X2
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373769.1 → XP_054229744.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373773.1 → XP_054229748.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373771.1 → XP_054229746.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373765.1 → XP_054229740.1 ubiquitin-protein ligase E3B isoform X1
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373768.1 → XP_054229743.1 ubiquitin-protein ligase E3B isoform X2
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373770.1 → XP_054229745.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373774.1 → XP_054229749.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373772.1 → XP_054229747.1 ubiquitin-protein ligase E3B isoform X3
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373775.1 → XP_054229750.1 ubiquitin-protein ligase E3B isoform X4
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373766.1 → XP_054229741.1 ubiquitin-protein ligase E3B isoform X1
- UniProtKB/TrEMBL
-
B9EK57
-
XM_054373780.1 → XP_054229755.1 ubiquitin-protein ligase E3B isoform X7
-
XM_054373781.1 → XP_054229756.1 ubiquitin-protein ligase E3B isoform X8
- UniProtKB/TrEMBL
-
F5H6D6
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_183414.1: Suppressed sequence
- Description
- NM_183414.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.