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    MAPKKK13 mitogen-activated protein kinase kinase kinase 13 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837226, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAPKKK13
    Official Full Name
    mitogen-activated protein kinase kinase kinase 13
    Primary source
    TAIR:AT1G07150
    Locus tag
    AT1G07150
    See related
    Araport:AT1G07150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10K1.14; F10K1_14; mitogen-activated protein kinase kinase kinase 13
    Summary
    member of MEKK subfamily
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    Genomic context

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    See MAPKKK13 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (2193941..2195996, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glycine-rich protein Neighboring gene Pleckstrin homology (PH) domain superfamily protein Neighboring gene Protein phosphatase 2C family protein Neighboring gene PHF5-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics. Sözen C, et al. Plant Cell, 2020 Jun. PMID 32265268, Free PMC Article
    2. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_100589.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 13
    NP_001184927.1
    • mitogen-activated protein kinase kinase kinase 13 (MAPKKK13); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: LP.04 four leaves visible, 4 anthesis, LP.10 ten leaves visible, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 14 (TAIR:AT2G30040.1).
    NP_172195.1
    • mitogen-activated protein kinase kinase kinase 13 (MAPKKK13); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: LP.04 four leaves visible, 4 anthesis, LP.10 ten leaves visible, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 14 (TAIR:AT2G30040.1); Has 115480 Blast hits to 114239 proteins in 3527 species: Archae - 169; Bacteria - 12227; Metazoa - 43932; Fungi - 11802; Plants - 28183; Viruses - 583; Other Eukaryotes - 18584 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2193941..2195996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001197998.1 → NP_001184927.1  mitogen-activated protein kinase kinase kinase 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184927.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WAF2, F4HNX7
      Conserved Domains (2) summary
      smart00220
      Location:9 → 265
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06606
      Location:9 → 265
      STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase

    2. NM_100589.3 → NP_172195.1  mitogen-activated protein kinase kinase kinase 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172195.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WAF2, Q9LMK8
      Conserved Domains (1) summary
      cd06606
      Location:23 → 279
      STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
    Nucleotide Protein
    Heading Accession and Version

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