zfp36l1b zinc finger protein 36, C3H type-like 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zfp36l1bprovided by ZNC
Official Full Name: zinc finger protein 36, C3H type-like 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2391
See related: Ensembl:ENSDARG00000021443 AllianceGenome:ZFIN:ZDB-GENE-030131-2391
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc06f10; zfp36l1l; zgc:77882; wu:fc06f10
Summary: Predicted to enable mRNA 3'-UTR AU-rich region binding activity and metal ion binding activity. Predicted to be involved in 3'-UTR-mediated mRNA destabilization and positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including epidermis; nervous system; neural crest; neural plate; and ventral mesoderm. Orthologous to human ZFP36L1 (ZFP36 ring finger protein like 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (9575374..9580450, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (9588134..9593210, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables mRNA 3'-UTR AU-rich region binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 3'-UTR-mediated mRNA destabilization	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mRNA decay activator protein ZFP36L1b

Names: CCCH zinc finger protein C3H-2; zinc finger protein 36, C3H type-like 1 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199649.2 → NP_955943.1 mRNA decay activator protein ZFP36L1b

See identical proteins and their annotated locations for NP_955943.1

Status: VALIDATED

Source sequence(s)

BC063991, BX649319

UniProtKB/TrEMBL

A0A8M1P9Y0, Q6P3H0

Related

ENSDARP00000011150.4, ENSDART00000014168.6

Conserved Domains (2) summary

pfam00642
Location:138 → 164

zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

pfam04553
Location:2 → 118

Tis11B_N; Tis11B like protein, N terminus