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    wbp2nl WBP2 N-terminal like [ Danio rerio (zebrafish) ]

    Gene ID: 325287, updated on 2-Nov-2024

    Summary

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    Official Symbol
    wbp2nlprovided by ZNC
    Official Full Name
    WBP2 N-terminal likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4012
    See related
    Ensembl:ENSDARG00000044852 AllianceGenome:ZFIN:ZDB-GENE-030131-4012
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wbp2; zgc:64061; wu:fc64g04
    Summary
    Predicted to enable chromatin DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human WBP2NL (WBP2 N-terminal like). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See wbp2nl in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (1223824..1228130)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (1455175..1459481)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene polymerase (DNA-directed), delta interacting protein 3 Neighboring gene ribosomal RNA processing 7 homolog A Neighboring gene si:ch1073-314i13.4 Neighboring gene uncharacterized LOC103910166

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish. Asakawa K, et al. Proc Natl Acad Sci U S A, 2008 Jan 29. PMID 18202183, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    postacrosomal sheath WW domain-binding protein
    Names
    WW domain binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199710.1 → NP_956004.1  postacrosomal sheath WW domain-binding protein

      See identical proteins and their annotated locations for NP_956004.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053232
      UniProtKB/TrEMBL
      A0A8M1PED4, F1QGY3, Q7T369
      Related
      ENSDARP00000065921.5, ENSDART00000065922.6
      Conserved Domains (2) summary
      cd13214
      Location:30 → 131
      PH-GRAM_WBP2; WW binding protein 2 (WB2) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam10349
      Location:101 → 197
      WWbp; WW-domain ligand protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      1223824..1228130
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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