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    Lockd lncRNA downstream of Cdkn1b [ Mus musculus (house mouse) ]

    Gene ID: 381822, updated on 9-Aug-2024

    Summary

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    Official Symbol
    Lockdprovided by MGI
    Official Full Name
    lncRNA downstream of Cdkn1bprovided by MGI
    Primary source
    MGI:MGI:1915081
    See related
    Ensembl:ENSMUSG00000098318 AllianceGenome:MGI:1915081
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Droc; 1190002F15Rik
    Expression
    Biased expression in liver E14 (RPKM 30.8), CNS E11.5 (RPKM 27.1) and 10 other tissues See more
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    Genomic context

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    See Lockd in Genome Data Viewer
    Location:
    6; 6 G1
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (134906055..134928681)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (134929092..134951718)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 19 Neighboring gene RIKEN cDNA 2810454H06 gene Neighboring gene CRISPRi-validated cis-regulatory element for Cdkn1b and Gpr19 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:134848417-134848526 Neighboring gene STARR-positive B cell enhancer ABC_E285 Neighboring gene cyclin dependent kinase inhibitor 1B Neighboring gene STARR-positive B cell enhancer mm9_chr6:134897243-134897544 Neighboring gene STARR-positive B cell enhancer mm9_chr6:134931598-134931898 Neighboring gene predicted gene, 36428 Neighboring gene apolipoprotein L domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E865 Neighboring gene DEAD box helicase 47

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Unlinking an lncRNA from Its Associated cis Element. Paralkar VR, et al. Mol Cell, 2016 Apr 7. PMID 27041223, Free PMC Article
    2. Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e translation. Chen X, et al. Cell Rep, 2022 Jun 7. PMID 35675771
    3. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Other Names

    • downstream lncRNA of Cdkn1b

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_037955.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site at the 5' end compared to variant 1.
      Source sequence(s)
      AI121041, AK004447

    2. NR_037956.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AI121041, AK004447
      Related
      ENSMUST00000184504.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      134906055..134928681
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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