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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001270452.2 → NP_001257381.1  testisin isoform 4 preproprotein
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses two alternate splice sites in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AA860356, AB031331, BI827608, BX454526
- UniProtKB/TrEMBL
-
I3L0U2
- Related
- ENSP00000458341.1, ENST00000574813.5
- Conserved Domains (2) summary
-
- smart00020
Location:41 → 194
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:42 → 184
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_006799.4 → NP_006790.1  testisin isoform 1 preproprotein
See identical proteins and their annotated locations for NP_006790.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB031331, AF058300
- Consensus CDS
-
CCDS10478.1
- UniProtKB/Swiss-Prot
- Q9NS34, Q9P2V6, Q9Y6M0
- UniProtKB/TrEMBL
-
I3L3C7
- Related
- ENSP00000005995.3, ENST00000005995.8
- Conserved Domains (1) summary
-
- cd00190
Location:42 → 283
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_144956.3 → NP_659205.1  testisin isoform 2 preproprotein
See identical proteins and their annotated locations for NP_659205.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AA860356, AB031331, BI334059, BX454526
- UniProtKB/TrEMBL
-
I3L3C7
- Related
- ENSP00000460351.1, ENST00000574265.1
- Conserved Domains (2) summary
-
- smart00020
Location:41 → 279
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:42 → 281
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_144957.3 → NP_659206.1  testisin isoform 3 preproprotein
See identical proteins and their annotated locations for NP_659206.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AA860356, AB031331, BX454526, CB529999
- Consensus CDS
-
CCDS45388.1
- UniProtKB/TrEMBL
-
I3L3C7
- Related
- ENSP00000407741.3, ENST00000450020.7
- Conserved Domains (2) summary
-
- smart00020
Location:41 → 267
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:42 → 269
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
RNA
-
NR_073012.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses two alternate splice sites, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AA860356, AB031331, BG717268, BX454526