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    dgcr6 DiGeorge syndrome critical region gene 6 [ Danio rerio (zebrafish) ]

    Gene ID: 403055, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dgcr6provided by ZNC
    Official Full Name
    DiGeorge syndrome critical region gene 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-125
    See related
    Ensembl:ENSDARG00000005500 AllianceGenome:ZFIN:ZDB-GENE-040912-125
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    DGCR6L; zgc:101841
    Summary
    Orthologous to several human genes including DGCR6 (DiGeorge syndrome critical region gene 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dgcr6 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (1636807..1649158, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (1588749..1601118, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496310 Neighboring gene uncharacterized LOC137496322 Neighboring gene rasGAP-activating-like protein 1 Neighboring gene phosphatidylinositol 4-kinase, catalytic, alpha b Neighboring gene serpin peptidase inhibitor, clade D (heparin cofactor), member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative mapping of the 22q11.2 deletion region and the potential of simple model organisms. Guna A, et al. J Neurodev Disord, 2015. PMID 26137170, Free PMC Article
    2. Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation. Campbell PD, et al. Mol Psychiatry, 2023 Sep. PMID 37794116, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC101841

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein DGCR6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205739.1 → NP_991302.1  protein DGCR6

      See identical proteins and their annotated locations for NP_991302.1

      Status: PROVISIONAL

      Source sequence(s)
      AY398335
      UniProtKB/TrEMBL
      F6NPI9, Q66IC0, Q6TH21
      Related
      ENSDARP00000027942.7, ENSDART00000026747.9
      Conserved Domains (1) summary
      pfam07324
      Location:10 → 194
      DGCR6; DiGeorge syndrome critical region 6 (DGCR6) protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      1636807..1649158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017357308.3 → XP_017212797.1  protein DGCR6 isoform X1

      UniProtKB/TrEMBL
      F6NPI9, Q66IC0, Q6TH21
      Related
      ENSDARP00000134769.1, ENSDART00000159705.2
      Conserved Domains (1) summary
      pfam07324
      Location:10 → 194
      DGCR6; DiGeorge syndrome critical region 6 (DGCR6) protein
    Nucleotide Protein
    Heading Accession and Version

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