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    LOC4328432 porphobilinogen deaminase, chloroplastic-like [ Oryza sativa Japonica Group (Japanese rice) ]

    Gene ID: 4328432, updated on 3-Dec-2024

    Summary

    Gene symbol
    LOC4328432
    Gene description
    porphobilinogen deaminase, chloroplastic-like
    Locus tag
    OSNPB_020168800
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Oryza sativa Japonica Group
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
    Also known as
    PBG; HEMC; HMBS; OsJ_05540
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    Genomic context

    See LOC4328432 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_06 current ASM3414082v1 (GCF_034140825.1) 2 NC_089036.1 (3724347..3727339)
    102 previous assembly IRGSP-1.0 (GCF_001433935.1) 2 NC_029257.1 (3715277..3718263)

    Chromosome 2 - NC_089036.1Genomic Context describing neighboring genes Neighboring gene OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 11 Neighboring gene peptidyl-prolyl cis-trans isomerase FKBP17-1, chloroplastic Neighboring gene uncharacterized protein C12B10.15c Neighboring gene uncharacterized LOC4328434

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydroxymethylbilane synthase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in peptidyl-pyrromethane cofactor linkage IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    porphobilinogen deaminase, chloroplastic
    Names
    Hydroxymethylbilane synthase
    LOC_Os02g07230
    P0669G09.15-1
    P0669G09.15-2
    Pre-uroporphyrinogen synthase
    putative porphobilinogen deaminase
    NP_001396270.1
    NP_001396271.1
    XP_015627258.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001409341.1NP_001396270.1  porphobilinogen deaminase, chloroplastic isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      CB653328, CB653329, CI006703, CI309942, CI318841, CI329212
      UniProtKB/Swiss-Prot
      A0A0P0VF64, Q6H6D1, Q6H6D2
      UniProtKB/TrEMBL
      B8AII1
    2. NM_001409342.1NP_001396271.1  porphobilinogen deaminase, chloroplastic isoform 2

      Status: VALIDATED

      Source sequence(s)
      CB653328, CB653329, CI006703, CI318841, CI329212
      UniProtKB/TrEMBL
      A0A0P0VFC8

    RefSeqs of Annotated Genomes: GCF_034140825.1-RS_2024_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM3414082v1 Primary Assembly

    Genomic

    1. NC_089036.1 Reference ASM3414082v1 Primary Assembly

      Range
      3724347..3727339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015771772.3XP_015627258.1  porphobilinogen deaminase, chloroplastic isoform X1

      UniProtKB/TrEMBL
      A0A0P0VFC8
      Conserved Domains (2) summary
      PRK00072
      Location:13303
      hemC; porphobilinogen deaminase; Reviewed
      cd13648
      Location:13283
      PBP2_PBGD_1; An uncharacterized subgroup of the PBGD family; the type 2 periplasmic binding protein fold