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    TEX12 testis expressed 12 [ Homo sapiens (human) ]

    Gene ID: 56158, updated on 27-Nov-2024

    Summary

    Official Symbol
    TEX12provided by HGNC
    Official Full Name
    testis expressed 12provided by HGNC
    Primary source
    HGNC:HGNC:11734
    See related
    Ensembl:ENSG00000150783 MIM:605791; AllianceGenome:HGNC:11734
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in testis (RPKM 7.9) and small intestine (RPKM 0.2) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TEX12 in Genome Data Viewer
    Location:
    11q23.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (112167372..112172556)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (112177701..112182885)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (112038095..112043279)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_18793 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_18795 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_18799 Neighboring gene interleukin 18 Neighboring gene Sharpr-MPRA regulatory region 14451 Neighboring gene uncharacterized LOC107987164 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:112048596-112048762 Neighboring gene beta-carotene oxygenase 2 Neighboring gene potassium channel tetramerization domain containing 9 pseudogene 4 Neighboring gene mitochondrial ribosomal protein S36 pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included genes: SDHD, BCO2

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in meiotic DNA repair synthesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in synaptonemal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in central element IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in central element ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in chromosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    testis-expressed protein 12
    Names
    testis expressed sequence 12

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031275.4NP_112565.1  testis-expressed protein 12

      See identical proteins and their annotated locations for NP_112565.1

      Status: REVIEWED

      Source sequence(s)
      AF285600, BC029506
      Consensus CDS
      CCDS31679.1
      UniProtKB/Swiss-Prot
      A6NDL9, B0YIX3, Q9BXU0
      UniProtKB/TrEMBL
      B0YIX2
      Related
      ENSP00000280358.4, ENST00000280358.5
      Conserved Domains (1) summary
      pfam15219
      Location:28122
      TEX12; Testis-expressed 12

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      112167372..112172556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      112177701..112182885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)