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    SILC1 sciatic injury induced lincRNA upregulator of SOX11 [ Homo sapiens (human) ]

    Gene ID: 150622, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SILC1provided by HGNC
    Official Full Name
    sciatic injury induced lincRNA upregulator of SOX11provided by HGNC
    Primary source
    HGNC:HGNC:26403
    See related
    AllianceGenome:HGNC:26403
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LINC01105
    Expression
    Restricted expression toward brain (RPKM 5.8) See more
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    Genomic context

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    See SILC1 in Genome Data Viewer
    Location:
    2p25.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (5932687..5980218)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (5954658..6002183)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (6072819..6120350)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268411 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:5865940-5866895 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:5881029-5881529 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:5937560-5938759 Neighboring gene long intergenic non-protein coding RNA 1810 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:6114361-6114862 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:6115742-6116395 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:6120871-6121617 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:6135557-6136756 Neighboring gene uncharacterized LOC400940 Neighboring gene microRNA 7158 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:6193971-6194712 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:6232422-6233621 Neighboring gene NANOG hESC enhancer GRCh37_chr2:6253851-6254352 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:6289007-6289241 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15240 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:6378134-6379333 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:6396128-6396341 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:6423042-6423564 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:6431337-6432536 Neighboring gene uncharacterized LOC105373401

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. MEG3, HCN3 and linc01105 influence the proliferation and apoptosis of neuroblastoma cells via the HIF-1α and p53 pathways. Tang W, et al. Sci Rep, 2016 Nov 8. PMID 27824082, Free PMC Article
    2. Regulation of Neuroregeneration by Long Noncoding RNAs. Perry RB, et al. Mol Cell, 2018 Nov 1. PMID 30401432, Free PMC Article
    3. Co-expression Network Analysis of Human lncRNAs and Cancer Genes. Cogill SB, et al. Cancer Inform, 2014. PMID 25392693, Free PMC Article
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • long intergenic non-protein coding RNA 1105

    Clone Names

    • MGC120893, DKFZp761K2322

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026832.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC073479, AC079770, DA139711

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      5932687..5980218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      5954658..6002183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153011.2: Suppressed sequence

      Description
      NM_153011.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein
    Heading Accession and Version

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