desi1a desumoylating isopeptidase 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: desi1aprovided by ZNC
Official Full Name: desumoylating isopeptidase 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1657
See related: Ensembl:ENSDARG00000033140 AllianceGenome:ZFIN:ZDB-GENE-040426-1657
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: desi2a; pppde2a; fam152ba; zgc:73066
Summary: Predicted to enable palmitoyl-(protein) hydrolase activity and peptidase activity. Predicted to be involved in protein export from nucleus and regulation of proteasomal ubiquitin-dependent protein catabolic process. Is expressed in nervous system and trigeminal placode. Orthologous to human DESI1 (desumoylating isopeptidase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (24973025..24979949, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (24842477..24849401, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables palmitoyl-(protein) hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of proteasomal ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: desumoylating isopeptidase 1

Names: PPPDE peptidase domain containing 2a; desumoylating isopeptidase 2a; family with sequence similarity 152, member Ba

NP_956994.1

EC 3.1.2.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.