trak2 trafficking protein, kinesin binding 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trak2provided by ZNC
Official Full Name: trafficking protein, kinesin binding 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7496
See related: Ensembl:ENSDARG00000102471 AllianceGenome:ZFIN:ZDB-GENE-030131-7496
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj21g01; wu:fj21g01
Summary: Predicted to enable GABA receptor binding activity and myosin binding activity. Predicted to be involved in several processes, including mitochondrion distribution; organelle transport along microtubule; and protein targeting. Predicted to be located in early endosome. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. Orthologous to human TRAK2 (trafficking kinesin protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (4184766..4228499, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (4024086..4067716, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fj21g01.x1 (e-PCR)
- UniSTS:198775

G39567 (e-PCR)
- UniSTS:23967

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GABA receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables myosin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in anterograde axonal transport of mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrion distribution	IBA Inferred from Biological aspect of Ancestor more info
involved_in neurogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic vesicle	IBA Inferred from Biological aspect of Ancestor more info
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
located_in early endosome	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: trafficking kinesin-binding protein 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

4184766..4228499 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005172086.5 → XP_005172143.1 trafficking kinesin-binding protein 2 isoform X2

UniProtKB/TrEMBL

A0A2R8Q3P3, A0A8M2BJC6

Related

ENSDARP00000147335.1, ENSDART00000179923.1

Conserved Domains (4) summary

pfam04849
Location:35 → 329

HAP1_N; HAP1 N-terminal conserved region

pfam07106
Location:250 → 332

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)

pfam12448
Location:403 → 530

Milton; Kinesin associated protein

cl23720
Location:182 → 311

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
XM_684210.10 → XP_689302.5 trafficking kinesin-binding protein 2 isoform X1

UniProtKB/TrEMBL

A0A0R4IDG7, A0A8N7T702

Related

ENSDARP00000133065.1, ENSDART00000162497.2

Conserved Domains (4) summary

pfam04849
Location:35 → 348

HAP1_N; HAP1 N-terminal conserved region

pfam07106
Location:269 → 351

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)

pfam12448
Location:422 → 549

Milton; Kinesin associated protein

cl23720
Location:201 → 330

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
XM_021476982.2 → XP_021332657.1 trafficking kinesin-binding protein 2 isoform X3

UniProtKB/TrEMBL

A0A2R8RYY2, A0A8M9PME8

Related

ENSDARP00000156274.1, ENSDART00000191433.1

Conserved Domains (2) summary

pfam04849
Location:38 → 295

HAP1_N; HAP1 N-terminal conserved region

pfam12448
Location:369 → 496

Milton; Kinesin associated protein
XM_005172089.5 → XP_005172146.1 trafficking kinesin-binding protein 2 isoform X4

UniProtKB/TrEMBL

A0A8M2BJY1

Conserved Domains (4) summary

TIGR04211
Location:57 → 158

SH3_and_anchor; SH3 domain protein

pfam07106
Location:202 → 276

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)

pfam12448
Location:347 → 474

Milton; Kinesin associated protein

pfam15619
Location:128 → 273

Lebercilin; Ciliary protein causing Leber congenital amaurosis disease