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    exoc6 exocyst complex component 6 [ Danio rerio (zebrafish) ]

    Gene ID: 406591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    exoc6provided by ZNC
    Official Full Name
    exocyst complex component 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2511
    See related
    Ensembl:ENSDARG00000020521 AllianceGenome:ZFIN:ZDB-GENE-040426-2511
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77548
    Summary
    Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to act upstream of or within intracellular protein transport. Predicted to be part of exocyst. Is expressed in nervous system; optic primordium; optic vesicle; ventral mesenchyme; and ventral mesoderm. Orthologous to human EXOC6 (exocyst complex component 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See exoc6 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (8968309..9087561, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (8930470..9049718, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene receptor accessory protein 3b Neighboring gene uncharacterized LOC108191699 Neighboring gene cytochrome P450, family 26, subfamily A, polypeptide 1 Neighboring gene ADAM metallopeptidase domain 8b Neighboring gene galanin receptor 2a-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis. Yin J, et al. BMC Genomics, 2014 Sep 30. PMID 25266257, Free PMC Article
    2. Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. Sanchez NE, et al. G3 (Bethesda), 2017 Oct 5. PMID 28855284, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vesicle tethering involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle tethering involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    exocyst complex component 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213300.1 → NP_998465.1  exocyst complex component 6

      See identical proteins and their annotated locations for NP_998465.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068986
      UniProtKB/TrEMBL
      Q6NTH9
      Related
      ENSDART00000022163.9
      Conserved Domains (2) summary
      pfam04091
      Location:464 → 706
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:92 → 177
      I_LWEQ; I/LWEQ domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      8968309..9087561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480047.2 → XP_021335722.1  exocyst complex component 6 isoform X5

      UniProtKB/TrEMBL
      A0A8M9PW59
      Conserved Domains (2) summary
      pfam04091
      Location:464 → 770
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:92 → 177
      I_LWEQ; I/LWEQ domain

    2. XM_005156065.5 → XP_005156122.1  exocyst complex component 6 isoform X6

      UniProtKB/TrEMBL
      A0A8M2B2X7
      Related
      ENSDARP00000112410.2, ENSDART00000125230.3
      Conserved Domains (2) summary
      pfam04091
      Location:462 → 768
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:90 → 175
      I_LWEQ; I/LWEQ domain

    3. XM_021480046.2 → XP_021335721.1  exocyst complex component 6 isoform X3

      UniProtKB/TrEMBL
      A0A8M9QIL5
      Conserved Domains (2) summary
      pfam04091
      Location:464 → 780
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:92 → 177
      I_LWEQ; I/LWEQ domain

    4. XM_005156063.4 → XP_005156120.1  exocyst complex component 6 isoform X4

      UniProtKB/TrEMBL
      A0A8M2B2D9
      Conserved Domains (2) summary
      pfam04091
      Location:464 → 770
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:92 → 177
      I_LWEQ; I/LWEQ domain

    5. XM_021480045.2 → XP_021335720.1  exocyst complex component 6 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QME7
      Conserved Domains (2) summary
      pfam04091
      Location:464 → 780
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:92 → 177
      I_LWEQ; I/LWEQ domain

    6. XM_017358444.3 → XP_017213933.1  exocyst complex component 6 isoform X7

      UniProtKB/TrEMBL
      A0A8M6Z1A1

    7. XM_005156061.5 → XP_005156118.1  exocyst complex component 6 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B218
      Conserved Domains (2) summary
      pfam04091
      Location:462 → 778
      Sec15; Exocyst complex subunit Sec15-like
      cl19756
      Location:90 → 175
      I_LWEQ; I/LWEQ domain
    Nucleotide Protein
    Heading Accession and Version

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