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    etaa1a ETAA1 activator of ATR kinase a [ Danio rerio (zebrafish) ]

    Gene ID: 558278, updated on 9-Dec-2024

    Summary

    Official Symbol
    etaa1aprovided by ZNC
    Official Full Name
    ETAA1 activator of ATR kinase aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080204-12
    See related
    Ensembl:ENSDARG00000074915 AllianceGenome:ZFIN:ZDB-GENE-080204-12
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    etaa1; zgc:171518
    Summary
    Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in DNA damage response; regulation of DNA damage checkpoint; and replication fork processing. Predicted to be active in nuclear replication fork. Orthologous to human ETAA1 (ETAA1 activator of ATR kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See etaa1a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (51536987..51546181)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (50884536..50902382)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene sprouty related EVH1 domain containing 2a Neighboring gene Meis homeobox 1 a Neighboring gene protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b Neighboring gene cannabinoid receptor interacting protein 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA damage checkpoint IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nuclear replication fork IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ewing's tumor-associated antigen 1
    Names
    ETAA1, ATR kinase activator
    Ewing tumor-associated antigen 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111157.2NP_001104627.2  ewing's tumor-associated antigen 1

      Status: VALIDATED

      Source sequence(s)
      CU929104
      UniProtKB/TrEMBL
      A8KB39
      Related
      ENSDARP00000126690.1, ENSDART00000152789.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      51536987..51546181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)