ufc1 ubiquitin-fold modifier conjugating enzyme 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ufc1provided by ZNC
Official Full Name: ubiquitin-fold modifier conjugating enzyme 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-268
See related: Ensembl:ENSDARG00000022340 AllianceGenome:ZFIN:ZDB-GENE-040801-268
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:100800
Summary: Predicted to enable UFM1 conjugating enzyme activity. Predicted to be involved in protein ufmylation; response to endoplasmic reticulum stress; and reticulophagy. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with spasticity and poor growth. Orthologous to human UFC1 (ubiquitin-fold modifier conjugating enzyme 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (57715614..57718850)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (57045397..57048633)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables UFM1 conjugating enzyme activity	IEA Inferred from Electronic Annotation more info
enables UFM1 conjugating enzyme activity	ISS Inferred from Sequence or Structural Similarity more info
enables UFM1 transferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein ufmylation	IEA Inferred from Electronic Annotation more info
involved_in protein ufmylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to endoplasmic reticulum stress	IBA Inferred from Biological aspect of Ancestor more info
involved_in reticulophagy	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ubiquitin-fold modifier-conjugating enzyme 1

Names: ufm1-conjugating enzyme 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.