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    eif4a1a eukaryotic translation initiation factor 4A1A [ Danio rerio (zebrafish) ]

    Gene ID: 386634, updated on 9-Dec-2024

    Summary

    Official Symbol
    eif4a1aprovided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 4A1Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031030-2
    See related
    Ensembl:ENSDARG00000092115 AllianceGenome:ZFIN:ZDB-GENE-031030-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    eif4a1; fb49a04; im:7143023; wu:fb20a10; wu:fb49a04; wu:fc76a02; wu:fc96c01; wu:fd15g03
    Summary
    Predicted to enable translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translational initiation. Is expressed in several structures, including immature eye; neural rod; neuromast; paraxial mesoderm; and somite. Orthologous to human EIF4A1 (eukaryotic translation initiation factor 4A1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See eif4a1a in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (26510532..26518089, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (26239339..26246896, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene mannose-P-dolichol utilization defect 1b Neighboring gene SRY-box transcription factor 19b Neighboring gene small nucleolar RNA SNORD10 Neighboring gene SUMO specific peptidase 3b Neighboring gene si:dkey-62k3.5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 4A1A
    Names
    eukaryotic translation initiation factor 4A
    NP_938180.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198366.2NP_938180.1  eukaryotic translation initiation factor 4A1A

      See identical proteins and their annotated locations for NP_938180.1

      Status: VALIDATED

      Source sequence(s)
      BC048899, CR848032, EB766529
      UniProtKB/TrEMBL
      A0A8M1PB73, Q802C9
      Related
      ENSDARP00000058912.4, ENSDART00000058913.5
      Conserved Domains (1) summary
      PTZ00424
      Location:20406
      PTZ00424; helicase 45; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      26510532..26518089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)