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    eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 541411, updated on 9-Dec-2024

    Summary

    Official Symbol
    eif4enif1provided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 4E nuclear import factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-113
    See related
    Ensembl:ENSDARG00000016177 AllianceGenome:ZFIN:ZDB-GENE-050320-113
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd15a05; wu:fd15a05; zgc:101646
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in negative regulation of translation. Predicted to act upstream of or within translational initiation. Part of protein-containing complex. Orthologous to human EIF4ENIF1 (eukaryotic translation initiation factor 4E nuclear import factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See eif4enif1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (40922320..40947671)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (40924760..40950135)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene saxiphilin Neighboring gene SFI1 centrin binding protein Neighboring gene POZ/BTB and AT hook containing zinc finger 1 Neighboring gene solute carrier family 2 member 11a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 4E transporter

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013538.1NP_001013556.1  eukaryotic translation initiation factor 4E transporter

      See identical proteins and their annotated locations for NP_001013556.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090823
      UniProtKB/TrEMBL
      A0A8M1N4U7, F6NXE9, Q5BL27
      Related
      ENSDARP00000023717.9, ENSDART00000002728.9
      Conserved Domains (1) summary
      pfam10477
      Location:25489
      EIF4E-T; Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      40922320..40947671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221718.1XP_068077819.1  eukaryotic translation initiation factor 4E transporter isoform X1

      UniProtKB/TrEMBL
      A0A8M9QFD8, E7FDR0
      Related
      ENSDARP00000113326.1, ENSDART00000133599.3