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    gfus.2 GDP-L-fucose synthase, tandem duplicate 2 [ Danio rerio (zebrafish) ]

    Gene ID: 445134, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gfus.2provided by ZNC
    Official Full Name
    GDP-L-fucose synthase, tandem duplicate 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-242
    See related
    Ensembl:ENSDARG00000039669 AllianceGenome:ZFIN:ZDB-GENE-041014-242
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gfusl1; tsta3l1; wu:fe16c04; zgc:100864; si:dkey-235d18.2
    Summary
    Predicted to enable GDP-L-fucose synthase activity. Predicted to be involved in 'de novo' GDP-L-fucose biosynthetic process. Predicted to act upstream of or within nucleotide-sugar biosynthetic process. Orthologous to human GFUS (GDP-L-fucose synthase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See gfus.2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (52492192..52525682)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (52686576..52720066)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 39 Neighboring gene GDP-L-fucose synthase, tandem duplicate 1 Neighboring gene pyrroline-5-carboxylate reductase 3 Neighboring gene eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GDP-L-fucose synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 'de novo' GDP-L-fucose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nucleotide-sugar biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    GDP-L-fucose synthase
    NP_001003528.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003528.1 → NP_001003528.1  GDP-L-fucose synthase

      See identical proteins and their annotated locations for NP_001003528.1

      Status: PREDICTED

      Source sequence(s)
      BC078246
      UniProtKB/TrEMBL
      A0A8M1N1F1, Q6DC41
      Related
      ENSDARP00000057985.5, ENSDART00000057986.7
      Conserved Domains (2) summary
      cd05239
      Location:16 → 319
      GDP_FS_SDR_e; GDP-fucose synthetase, extended (e) SDRs
      pfam01370
      Location:17 → 249
      Epimerase; NAD dependent epimerase/dehydratase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      52492192..52525682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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