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    hmgb3b high mobility group box 3b [ Danio rerio (zebrafish) ]

    Gene ID: 550466, updated on 9-Dec-2024

    Summary

    Official Symbol
    hmgb3bprovided by ZNC
    Official Full Name
    high mobility group box 3bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-290
    See related
    Ensembl:ENSDARG00000006408 AllianceGenome:ZFIN:ZDB-GENE-050417-290
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hmgb3; fa19b06; fj43d02; wu:fa19b06; wu:fj43d02; zgc:112073
    Summary
    Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Is expressed in central nervous system; intermediate cell mass of mesoderm; ovary; pectoral fin bud; and telencephalon. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hmgb3b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (34119789..34129776)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (34085299..34095286)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene zgc:110222 Neighboring gene myotubularin related protein 1b Neighboring gene transient receptor potential cation channel, subfamily C, member 5b Neighboring gene ALG13 UDP-N-acetylglucosaminyltransferase subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    high mobility group protein B3b
    Names
    high-mobility group box 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017769.1NP_001017769.1  high mobility group protein B3b

      See identical proteins and their annotated locations for NP_001017769.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093186
      UniProtKB/TrEMBL
      Q567G0
      Related
      ENSDARP00000007566.6, ENSDART00000024750.8
      Conserved Domains (2) summary
      pfam00505
      Location:94161
      HMG_box; HMG (high mobility group) box
      pfam09011
      Location:778
      HMG_box_2; HMG-box domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      34119789..34129776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)