fnta farnesyltransferase, CAAX box, subunit alpha [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fntaprovided by ZNC
Official Full Name: farnesyltransferase, CAAX box, subunit alphaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-866
See related: Ensembl:ENSDARG00000099143 AllianceGenome:ZFIN:ZDB-GENE-030131-866
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:6909421; wu:fb51d12; wu:fz92f09; zgc:158397
Summary: Predicted to enable protein prenyltransferase activity. Predicted to contribute to CAAX-protein geranylgeranyltransferase activity and protein farnesyltransferase activity. Predicted to be involved in peptide pheromone maturation. Predicted to act upstream of or within protein prenylation. Predicted to be part of CAAX-protein geranylgeranyltransferase complex and protein farnesyltransferase complex. Predicted to be active in cytoplasm. Orthologous to human FNTA (farnesyltransferase, CAAX box, subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (3516560..3537129)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (3409254..3429823)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb51d12.x1 (e-PCR)
- UniSTS:203267

fj10d11.y1 (e-PCR)
- UniSTS:198501

AI477282 (e-PCR)
- UniSTS:206495

fj86h08.y1 (e-PCR)
- UniSTS:200171

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
contributes_to CAAX-protein geranylgeranyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables CAAX-protein geranylgeranyltransferase activity	IEA Inferred from Electronic Annotation more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
contributes_to protein farnesyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein farnesyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptide pheromone maturation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein prenylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CAAX-protein geranylgeranyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of protein farnesyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Names: farnesyltransferase, CAAX box, alpha

NP_001074029.1

EC 2.5.1.58

EC 2.5.1.59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.