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    ccar2 cell cycle and apoptosis regulator 2 [ Danio rerio (zebrafish) ]

    Gene ID: 564155, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ccar2provided by ZNC
    Official Full Name
    cell cycle and apoptosis regulator 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-207
    See related
    Ensembl:ENSDARG00000038302 AllianceGenome:ZFIN:ZDB-GENE-091204-207
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-24n17.5
    Summary
    Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human CCAR2 (cell cycle and apoptosis regulator 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ccar2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (2876001..2898724)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (2848789..2871237)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene YKT6 v-SNARE homolog (S. cerevisiae) Neighboring gene DEAD (Asp-Glu-Ala-Asp) box helicase 56 Neighboring gene endoplasmic reticulum aminopeptidase 1a Neighboring gene occludin a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cell cycle and apoptosis regulator protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      2876001..2898724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005155529.5 → XP_005155586.1  cell cycle and apoptosis regulator protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005155586.1

      UniProtKB/TrEMBL
      A0A8N7UVX0
      Conserved Domains (2) summary
      pfam14443
      Location:309 → 417
      DBC1; DBC1
      pfam14444
      Location:12 → 64
      S1-like; S1-like

    2. XM_005155531.5 → XP_005155588.1  cell cycle and apoptosis regulator protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B1L7, E7FGT1, E9QH28
      Related
      ENSDARP00000115210.1, ENSDART00000140803.4
      Conserved Domains (2) summary
      pfam14443
      Location:309 → 417
      DBC1; DBC1
      pfam14444
      Location:12 → 64
      S1-like; S1-like

    3. XM_005155530.5 → XP_005155587.1  cell cycle and apoptosis regulator protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005155587.1

      UniProtKB/TrEMBL
      A0A8N7UVX0
      Conserved Domains (2) summary
      pfam14443
      Location:309 → 417
      DBC1; DBC1
      pfam14444
      Location:12 → 64
      S1-like; S1-like

    4. XM_687505.8 → XP_692597.4  cell cycle and apoptosis regulator protein 2 isoform X1

      See identical proteins and their annotated locations for XP_692597.4

      UniProtKB/TrEMBL
      A0A8N7UVX0
      Conserved Domains (2) summary
      pfam14443
      Location:309 → 417
      DBC1; DBC1
      pfam14444
      Location:12 → 64
      S1-like; S1-like

    5. XM_068223884.1 → XP_068079985.1  cell cycle and apoptosis regulator protein 2 isoform X3

      Related
      ENSDARP00000155580.1, ENSDART00000192083.1

    6. XM_021479232.2 → XP_021334907.1  cell cycle and apoptosis regulator protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PTS0
      Conserved Domains (2) summary
      pfam14443
      Location:305 → 413
      DBC1
      pfam14444
      Location:8 → 60
      S1-like
    Nucleotide Protein
    Heading Accession and Version

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