trmt2b tRNA methyltransferase 2 homolog B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trmt2bprovided by ZNC
Official Full Name: tRNA methyltransferase 2 homolog Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050809-101
See related: Ensembl:ENSDARG00000033967 AllianceGenome:ZFIN:ZDB-GENE-050809-101
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7160396; wu:fc49d02; zgc:162982
Summary: Predicted to enable rRNA (uridine-C5-)-methyltransferase activity and tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent. Predicted to act upstream of or within methylation; rRNA processing; and tRNA processing. Predicted to be active in mitochondrion. Orthologous to human TRMT2B (tRNA methyltransferase 2 homolog B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (30033036..30034787, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (29902586..29904304, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI657718 (e-PCR)
- UniSTS:206099

fc49d02 (e-PCR), detects polymorphism
- UniSTS:189251

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables rRNA (uridine-C5-)-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent	IEA Inferred from Electronic Annotation more info
enables tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: tRNA (uracil-5-)-methyltransferase homolog B

Names: DKEYP-115D2.4; TRM2 homolog B; TRM2 tRNA methyltransferase 2 homolog B; rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA (uracil(54)-C(5))-methyltransferase homolog-B; tRNA (uracil-5-)-methyltransferase homolog; tRNA (uracil-5-)-methyltransferase homolog-B

NP_001116415.2

EC 2.1.1.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.