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    c1qtnf5 C1q and TNF related 5 [ Danio rerio (zebrafish) ]

    Gene ID: 555815, updated on 9-Dec-2024

    Summary

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    Official Symbol
    c1qtnf5provided by ZNC
    Official Full Name
    C1q and TNF related 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050706-101
    See related
    Ensembl:ENSDARG00000056134 AllianceGenome:ZFIN:ZDB-GENE-050706-101
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb02c10; wu:fb02f05; zgc:112378
    Summary
    Predicted to be located in extracellular region. Is expressed in eye. Human ortholog(s) of this gene implicated in late-onset retinal degeneration. Orthologous to human C1QTNF5 (C1q and TNF related 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See c1qtnf5 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (23369020..23376543, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (23433755..23441278, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene melanoma cell adhesion molecule b Neighboring gene ring finger protein 26 Neighboring gene lysine (K)-specific methyltransferase 2A Neighboring gene ubiquitination factor E4A (UFD2 homolog, yeast)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages. Collery RF, et al. Invest Ophthalmol Vis Sci, 2016 Dec 1. PMID 28002843, Free PMC Article
    2. Characterization of the Zebrafish Cell Landscape at Single-Cell Resolution. Jiang M, et al. Front Cell Dev Biol, 2021. PMID 34660600, Free PMC Article
    3. Transcriptional signature of accessory cells in the lateral line, using the Tnk1bp1:EGFP transgenic zebrafish line. Behra M, et al. BMC Dev Biol, 2012 Jan 24. PMID 22273551, Free PMC Article
    4. Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line. Steiner AB, et al. Proc Natl Acad Sci U S A, 2014 Apr 8. PMID 24706895, Free PMC Article
    5. Characterization of C1q in teleosts: insight into the molecular and functional evolution of C1q family and classical pathway. Hu YL, et al. J Biol Chem, 2010 Sep 10. PMID 20615881, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112378

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    complement C1q tumor necrosis factor-related protein 5
    Names
    C1q and tumor necrosis factor related protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001029953.1 → NP_001025124.1  complement C1q tumor necrosis factor-related protein 5 precursor

      See identical proteins and their annotated locations for NP_001025124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098626
      UniProtKB/TrEMBL
      A0A8M1N7C2, Q4KMC6
      Related
      ENSDARP00000073031.4, ENSDART00000078570.5
      Conserved Domains (2) summary
      pfam01391
      Location:34 → 102
      Collagen; Collagen triple helix repeat (20 copies)
      pfam00386
      Location:109 → 237
      C1q; C1q domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      23369020..23376543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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