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    hoxb7a homeobox B7a [ Danio rerio (zebrafish) ]

    Gene ID: 58044, updated on 9-Dec-2024

    Summary

    Official Symbol
    hoxb7aprovided by ZNC
    Official Full Name
    homeobox B7aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000329-2
    See related
    Ensembl:ENSDARG00000056030 AllianceGenome:ZFIN:ZDB-GENE-000329-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hoxb7; z-139; fc39g02; wu:fc39g02
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including mesoderm; neural tube; oocyte; somite; and tail bud. Orthologous to human HOXB7 (homeobox B7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hoxb7a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (23691787..23696273)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (23561166..23565725)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103910246 Neighboring gene homeobox B9a Neighboring gene homeobox B8a Neighboring gene homeobox B3a Neighboring gene homeobox B6a Neighboring gene homeobox B5a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in anterior/posterior pattern specification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    homeobox protein Hox-B7a
    Names
    homeo box B7a
    homeobox gene B-7
    hox-B7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115091.2NP_001108563.1  homeobox protein Hox-B7a

      See identical proteins and their annotated locations for NP_001108563.1

      Status: VALIDATED

      Source sequence(s)
      BC163361, BX927395
      UniProtKB/Swiss-Prot
      O57362, Q4PRA1, Q8AWY9
      UniProtKB/TrEMBL
      B3DJ48
      Related
      ENSDARP00000072915.4, ENSDART00000078453.5
      Conserved Domains (1) summary
      pfam00046
      Location:149201
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      23691787..23696273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)