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    acy3.2 aspartoacylase (aminocyclase) 3, tandem duplicate 2 [ Danio rerio (zebrafish) ]

    Gene ID: 436619, updated on 2-Nov-2024

    Summary

    Official Symbol
    acy3.2provided by ZNC
    Official Full Name
    aspartoacylase (aminocyclase) 3, tandem duplicate 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-37
    See related
    Ensembl:ENSDARG00000005525 AllianceGenome:ZFIN:ZDB-GENE-040718-37
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92178; id:ibd5047
    Summary
    Predicted to enable aminoacylase activity. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in cytosol. Is expressed in pronephric duct; pronephric mesoderm; and pronephros. Orthologous to human ACY3 (aminoacylase 3). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See acy3.2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (52490365..52497943, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (51855649..51863228, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene galactosidase, beta 1 Neighboring gene claudin domain containing 1b Neighboring gene uncharacterized LOC108190353 Neighboring gene aspartoacylase (aminocyclase) 3, tandem duplicate 1 Neighboring gene tachykinin receptor 3-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables aminoacylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) B
    Names
    ACY-3.2
    aminoacylase-3.2
    aspartoacylase (aminocyclase) 3.2
    aspartoacylase-2B
    NP_001002347.1
    XP_021326628.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002347.1NP_001002347.1  N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) B

      See identical proteins and their annotated locations for NP_001002347.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075914
      UniProtKB/Swiss-Prot
      A2BG59, Q6DHQ3
      UniProtKB/TrEMBL
      A0A8M9PI40
      Related
      ENSDARP00000023827.7, ENSDART00000004233.9
      Conserved Domains (1) summary
      cd06909
      Location:12301
      M14_ASPA; Peptidase M14 Aspartoacylase (ASPA) subfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      52490365..52497943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470953.2XP_021326628.1  N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) B isoform X1

      UniProtKB/Swiss-Prot
      A2BG59, Q6DHQ3
      UniProtKB/TrEMBL
      A0A8M9PI40
      Conserved Domains (1) summary
      cd06909
      Location:12301
      M14_ASPA; Peptidase M14 Aspartoacylase (ASPA) subfamily