TIA1 TIA1 cytotoxic granule associated RNA binding protein [Homo sapiens (human)] - Gene

Summary

Official Symbol: TIA1provided by HGNC
Official Full Name: TIA1 cytotoxic granule associated RNA binding proteinprovided by HGNC
Primary source: HGNC:HGNC:11802
See related: Ensembl:ENSG00000116001 MIM:603518; AllianceGenome:HGNC:11802
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: WDM; ALS26; TIA-1
Summary: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]
Expression: Ubiquitous expression in endometrium (RPKM 25.4), ovary (RPKM 18.9) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 2p13.3

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	2	NC_000002.12 (70209444..70248793, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	2	NC_060926.1 (70221187..70260535, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	2	NC_000002.11 (70436576..70475925, complement)

Chromosome 2 - NC_000002.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Defining the landscape of TIA1 and SQSTM1 digenic myopathy.
Title: Defining the landscape of TIA1 and SQSTM1 digenic myopathy.
The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics.
Title: The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics.
RAMP2-AS1 stabilized RAPM2 mRNA through TIA1 to inhibit the progression of non-small cell lung cancer.
Title: RAMP2-AS1 stabilized RAPM2 mRNA through TIA1 to inhibit the progression of non-small cell lung cancer.
Distal myopathy due to digenic inheritance of TIA1 and SQSTM1 variants in two unrelated Spanish patients.
Title: Distal myopathy due to digenic inheritance of TIA1 and SQSTM1 variants in two unrelated Spanish patients.
Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein.
Title: Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein.
The role of peritumoral CD8 + /TIA1 + lymphocytes in hepatocellular carcinoma aggressiveness and recurrence after surgical resection.
Title: The role of peritumoral CD8 + /TIA1 + lymphocytes in hepatocellular carcinoma aggressiveness and recurrence after surgical resection.
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures.
Title: ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures.
Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling.
Title: Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling.
Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA-1.
Title: Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA-1.
The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease.
Title: The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease.

Submit: New GeneRIF Correction See all GeneRIFs (80)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia MedGen: C5436882 OMIM: 619133 GeneReviews: Not available	Compare labs
Welander distal myopathy MedGen: C0221054 OMIM: 604454 GeneReviews: Not available	Compare labs

EBI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Protein interactions

Protein	Gene	Interaction	Pubs
Tat	tat	HIV-1 Tat co-localizes with TIA1 in cytoplasmic stress granules under stress conditions	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

WI-21718 (e-PCR)
- UniSTS:65067

D2S303 (e-PCR)
- UniSTS:14946

D2S303 (e-PCR)
- UniSTS:82055

SHGC-58269 (e-PCR)
- UniSTS:34198

RH68286 (e-PCR)
- UniSTS:70340

WI-11889 (e-PCR)
- UniSTS:3530

RH48876 (e-PCR)
- UniSTS:48595

RH47301 (e-PCR)
- UniSTS:12500

SHGC-64100 (e-PCR)
- UniSTS:34519

SHGC-32459 (e-PCR)
- UniSTS:15067

D2S1873 (e-PCR)
- UniSTS:153565

RH81041 (e-PCR)
- UniSTS:86501

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables RNA binding	HDA more info	PubMed
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables mRNA 3'-UTR AU-rich region binding	IEA Inferred from Electronic Annotation more info
enables mRNA 3'-UTR binding	ISS Inferred from Sequence or Structural Similarity more info
enables poly(A) binding	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cytokine production	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of translation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of epithelial cell apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in protein localization to cytoplasmic stress granule	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of mRNA splicing, via spliceosome	IDA Inferred from Direct Assay more info	PubMed
involved_in stress granule assembly	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic stress granule	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	IDA Inferred from Direct Assay more info
located_in nuclear stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in nucleoplasm	IDA Inferred from Direct Assay more info
located_in nucleoplasm	TAS Traceable Author Statement more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytotoxic granule associated RNA binding protein TIA1

Names: T-cell-restricted intracellular antigen-1; p40-TIA-1 (containing p15-TIA-1)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_029967.1 RefSeqGene

Range

5020..44204

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001351508.2 → NP_001338437.1 cytotoxic granule associated RNA binding protein TIA1 isoform 3

Status: REVIEWED

Source sequence(s)

AC016700

Consensus CDS

CCDS86847.1

UniProtKB/TrEMBL

F8W8I6, Q59G98

Related

ENSP00000282574.4, ENST00000282574.8

Conserved Domains (3) summary

cd12620
Location:214 → 286

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12615
Location:8 → 81

RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12618
Location:104 → 181

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
NM_001351509.2 → NP_001338438.1 cytotoxic granule associated RNA binding protein TIA1 isoform 4

Status: REVIEWED

Source sequence(s)

AC016700

UniProtKB/TrEMBL

Q59G98

Conserved Domains (3) summary

cd12618
Location:96 → 175

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12621
Location:205 → 278

RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:8 → 83

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351510.2 → NP_001338439.1 cytotoxic granule associated RNA binding protein TIA1 isoform 5

Status: REVIEWED

Source sequence(s)

AC016700

UniProtKB/TrEMBL

Q59G98

Conserved Domains (3) summary

cd12620
Location:203 → 275

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12615
Location:8 → 81

RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12618
Location:93 → 170

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
NM_001351511.1 → NP_001338440.1 cytotoxic granule associated RNA binding protein TIA1 isoform 6

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (3) summary

TIGR01628
Location:11 → 342

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd12620
Location:177 → 249

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12618
Location:67 → 144

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
NM_001351512.1 → NP_001338441.1 cytotoxic granule associated RNA binding protein TIA1 isoform 7

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (3) summary

cd12618
Location:59 → 138

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12621
Location:168 → 241

RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl25887
Location:13 → 333

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
NM_001351513.1 → NP_001338442.1 cytotoxic granule associated RNA binding protein TIA1 isoform 8

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (3) summary

cd12618
Location:57 → 136

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12621
Location:166 → 239

RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl25887
Location:11 → 331

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
NM_001351514.2 → NP_001338443.1 cytotoxic granule associated RNA binding protein TIA1 isoform 9

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (3) summary

cd12618
Location:29 → 108

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12621
Location:138 → 211

RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:1 → 23

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351515.2 → NP_001338444.1 cytotoxic granule associated RNA binding protein TIA1 isoform 10

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (2) summary

cd12620
Location:113 → 185

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12618
Location:3 → 80

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
NM_001351516.2 → NP_001338445.1 cytotoxic granule associated RNA binding protein TIA1 isoform 11

Status: REVIEWED

Source sequence(s)

AC016700

UniProtKB/TrEMBL

C9JTN7

Related

ENSP00000399567.1, ENST00000445587.5

Conserved Domains (2) summary

cd12618
Location:105 → 184

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:8 → 81

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351517.2 → NP_001338446.1 cytotoxic granule associated RNA binding protein TIA1 isoform 12

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (2) summary

cl17169
Location:74 → 147

RRM_SF; RNA recognition motif (RRM) superfamily

cl25887
Location:4 → 238

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
NM_001351518.2 → NP_001338447.1 cytotoxic granule associated RNA binding protein TIA1 isoform 13

Status: REVIEWED

Source sequence(s)

AC016700, BC015944

Consensus CDS

CCDS86846.1

Related

ENSP00000413751.2, ENST00000416149.6

Conserved Domains (2) summary

cd12618
Location:105 → 184

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:8 → 81

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351519.2 → NP_001338448.1 cytotoxic granule associated RNA binding protein TIA1 isoform 14

Status: REVIEWED

Source sequence(s)

AC016700

UniProtKB/TrEMBL

H7BY49

Conserved Domains (1) summary

TIGR01628
Location:9 → 156

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
NM_001351520.2 → NP_001338449.1 cytotoxic granule associated RNA binding protein TIA1 isoform 15

Status: REVIEWED

Source sequence(s)

AC016700

Related

ENST00000477044.6

Conserved Domains (1) summary

cl17169
Location:8 → 83

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351521.2 → NP_001338450.1 cytotoxic granule associated RNA binding protein TIA1 isoform 16

Status: REVIEWED

Source sequence(s)

AC016700

UniProtKB/TrEMBL

H7BY49

Related

ENSP00000354838.4, ENST00000361692.4

Conserved Domains (1) summary

cl17169
Location:8 → 81

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351522.2 → NP_001338451.1 cytotoxic granule associated RNA binding protein TIA1 isoform 17

Status: REVIEWED

Source sequence(s)

AC016700

Consensus CDS

CCDS86848.1

UniProtKB/TrEMBL

E5RGV5

Related

ENSP00000430969.1, ENST00000474809.6

Conserved Domains (2) summary

cd12615
Location:8 → 81

RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:104 → 133

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351523.2 → NP_001338452.1 cytotoxic granule associated RNA binding protein TIA1 isoform 18

Status: REVIEWED

Source sequence(s)

AC016700

Conserved Domains (1) summary

cl17169
Location:29 → 82

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351524.2 → NP_001338453.1 cytotoxic granule associated RNA binding protein TIA1 isoform 19

Status: REVIEWED

Description

Transcript Variant: This variant (19), as well as variant 20, encodes isoform 19.

Source sequence(s)

AC016700

Conserved Domains (3) summary

TIGR01628
Location:4 → 239

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd12620
Location:74 → 146

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cl17169
Location:1 → 41

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001351525.2 → NP_001338454.1 cytotoxic granule associated RNA binding protein TIA1 isoform 19

Status: REVIEWED

Description

Transcript Variant: This variant (20), as well as variant 19, encodes isoform 19.

Source sequence(s)

AC016700

Conserved Domains (3) summary

TIGR01628
Location:4 → 239

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd12620
Location:74 → 146

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cl17169
Location:1 → 41

RRM_SF; RNA recognition motif (RRM) superfamily
NM_022037.4 → NP_071320.2 cytotoxic granule associated RNA binding protein TIA1 isoform 1

See identical proteins and their annotated locations for NP_071320.2

Status: REVIEWED

Description

Transcript Variant: This variant (1) is missing exon 5, which is included in transcript variant 2, resulting in the shorter isoform (1).

Source sequence(s)

AC016700

Consensus CDS

CCDS1900.1

UniProtKB/TrEMBL

Q59G98

Related

ENSP00000404023.2, ENST00000415783.6

Conserved Domains (3) summary

cd12620
Location:203 → 275

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12615
Location:8 → 81

RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12618
Location:93 → 170

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
NM_022173.4 → NP_071505.2 cytotoxic granule associated RNA binding protein TIA1 isoform 2

See identical proteins and their annotated locations for NP_071505.2

Status: REVIEWED

Description

Transcript Variant: This variant (2) includes exon 5, which is missing in transcript variant 1, resulting in the longer isoform (2).

Source sequence(s)

AC016700

Consensus CDS

CCDS1901.1

UniProtKB/Swiss-Prot

P31483, Q53SS9, Q96B58

UniProtKB/TrEMBL

Q59G98

Related

ENSP00000401371.2, ENST00000433529.7

Conserved Domains (3) summary

cd12620
Location:214 → 286

RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins

cd12615
Location:8 → 81

RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12618
Location:104 → 181

RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

RNA

NR_147216.1 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147217.1 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147218.1 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147219.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147220.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147221.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147222.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147223.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147224.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147225.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147226.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147227.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147228.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147229.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147230.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147231.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700
NR_147232.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AC016700

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000002.12 Reference GRCh38.p14 Primary Assembly

Range

70209444..70248793 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005264528.6 → XP_005264585.1 cytotoxic granule associated RNA binding protein TIA1 isoform X1

See identical proteins and their annotated locations for XP_005264585.1

Conserved Domains (3) summary

cd12618
Location:40 → 119

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12621
Location:149 → 222

RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cl17169
Location:1 → 23

RRM_SF; RNA recognition motif (RRM) superfamily
XM_047445625.1 → XP_047301581.1 cytotoxic granule associated RNA binding protein TIA1 isoform X2
XM_047445630.1 → XP_047301586.1 cytotoxic granule associated RNA binding protein TIA1 isoform X5
XM_047445628.1 → XP_047301584.1 cytotoxic granule associated RNA binding protein TIA1 isoform X4
XM_047445626.1 → XP_047301582.1 cytotoxic granule associated RNA binding protein TIA1 isoform X2
XM_047445632.1 → XP_047301588.1 cytotoxic granule associated RNA binding protein TIA1 isoform X6
XM_047445631.1 → XP_047301587.1 cytotoxic granule associated RNA binding protein TIA1 isoform X6
XM_047445627.1 → XP_047301583.1 cytotoxic granule associated RNA binding protein TIA1 isoform X3
XM_047445629.1 → XP_047301585.1 cytotoxic granule associated RNA binding protein TIA1 isoform X4
XM_047445634.1 → XP_047301590.1 cytotoxic granule associated RNA binding protein TIA1 isoform X7
XM_047445633.1 → XP_047301589.1 cytotoxic granule associated RNA binding protein TIA1 isoform X7

Alternate T2T-CHM13v2.0

Genomic

NC_060926.1 Alternate T2T-CHM13v2.0

Range

70221187..70260535 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054343587.1 → XP_054199562.1 cytotoxic granule associated RNA binding protein TIA1 isoform X1
XM_054343588.1 → XP_054199563.1 cytotoxic granule associated RNA binding protein TIA1 isoform X2
XM_054343593.1 → XP_054199568.1 cytotoxic granule associated RNA binding protein TIA1 isoform X5
XM_054343591.1 → XP_054199566.1 cytotoxic granule associated RNA binding protein TIA1 isoform X4
XM_054343589.1 → XP_054199564.1 cytotoxic granule associated RNA binding protein TIA1 isoform X2
XM_054343595.1 → XP_054199570.1 cytotoxic granule associated RNA binding protein TIA1 isoform X6
XM_054343594.1 → XP_054199569.1 cytotoxic granule associated RNA binding protein TIA1 isoform X6
XM_054343590.1 → XP_054199565.1 cytotoxic granule associated RNA binding protein TIA1 isoform X3
XM_054343592.1 → XP_054199567.1 cytotoxic granule associated RNA binding protein TIA1 isoform X4
XM_054343597.1 → XP_054199572.1 cytotoxic granule associated RNA binding protein TIA1 isoform X7
XM_054343596.1 → XP_054199571.1 cytotoxic granule associated RNA binding protein TIA1 isoform X7