U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PSME3IP1 proteasome activator subunit 3 interacting protein 1 [ Homo sapiens (human) ]

    Gene ID: 80011, updated on 9-Dec-2024

    Summary

    Official Symbol
    PSME3IP1provided by HGNC
    Official Full Name
    proteasome activator subunit 3 interacting protein 1provided by HGNC
    Primary source
    HGNC:HGNC:29856
    See related
    Ensembl:ENSG00000172775 MIM:617766; AllianceGenome:HGNC:29856
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CDA10; NIP30; PIP30; CDA018; FAM192A; C16orf94
    Summary
    Involved in negative regulation of proteasomal protein catabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in brain (RPKM 12.2), testis (RPKM 10.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PSME3IP1 in Genome Data Viewer
    Location:
    16q13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (57152466..57186116, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (62948740..62982387, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (57186378..57220028, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10872 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10873 Neighboring gene NLR family CARD domain containing 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10874 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57060363-57060881 Neighboring gene CFAP69 pseudogene 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_43539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10875 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10876 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10877 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10878 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10879 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10880 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:57095254-57096453 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57103335-57104060 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57104061-57104785 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10881 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7519 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7522 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7520 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7521 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57137039-57137994 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57139274-57139873 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10882 Neighboring gene copine 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10883 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7523 Neighboring gene Sharpr-MPRA regulatory region 3054 Neighboring gene Sharpr-MPRA regulatory region 6435 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57183845-57184634 Neighboring gene NANOG hESC enhancer GRCh37_chr16:57212532-57213113 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10884 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7524 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:57220937-57221581 Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_43594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10885 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7525 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7526 Neighboring gene uncharacterized LOC124903697 Neighboring gene ARF like GTPase 2 binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ21799, MGC74898

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    PSME3-interacting protein
    Names
    NEFA-interacting nuclear protein NIP30
    PA28G interacting protein 30kDa
    PA28G-interacting protein
    PSME3 interacting protein 30kDa
    family with sequence similarity 192 member A
    protein FAM192A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001354078.1NP_001341007.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    2. NM_001354079.1NP_001341008.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    3. NM_001354080.1NP_001341009.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Related
      ENSP00000457740.1, ENST00000569266.5
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    4. NM_001354081.2NP_001341010.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    5. NM_001354082.1NP_001341011.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    6. NM_001354083.2NP_001341012.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Related
      ENSP00000457850.1, ENST00000567439.5
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    7. NM_001354084.2NP_001341013.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    8. NM_001354085.2NP_001341014.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    9. NM_001354086.2NP_001341015.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    10. NM_001354087.1NP_001341016.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    11. NM_001354088.2NP_001341017.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    12. NM_001354089.2NP_001341018.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    13. NM_001354090.2NP_001341019.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    14. NM_001354091.2NP_001341020.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    15. NM_001354092.2NP_001341021.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    16. NM_001354094.2NP_001341023.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    17. NM_001354095.2NP_001341024.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    18. NM_001354096.2NP_001341025.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    19. NM_001354097.2NP_001341026.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    20. NM_001354098.2NP_001341027.1  PSME3-interacting protein isoform b

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Conserved Domains (1) summary
      pfam10187
      Location:41129
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    21. NM_001354099.2NP_001341028.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    22. NM_001354100.2NP_001341029.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    23. NM_001354101.2NP_001341030.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    24. NM_001354102.2NP_001341031.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    25. NM_001354103.2NP_001341032.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC009090
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    26. NM_024946.4NP_079222.1  PSME3-interacting protein isoform a

      See identical proteins and their annotated locations for NP_079222.1

      Status: VALIDATED

      Source sequence(s)
      AC009090, BC020536, CA308353, DB101263
      Consensus CDS
      CCDS42168.1
      UniProtKB/Swiss-Prot
      Q9GZU8
      Related
      ENSP00000335808.6, ENST00000309137.13
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      57152466..57186116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047434681.1XP_047290637.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    2. XM_047434680.1XP_047290636.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    3. XM_047434679.1XP_047290635.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    4. XM_047434678.1XP_047290634.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    5. XM_047434676.1XP_047290632.1  PSME3-interacting protein isoform X2

    6. XM_047434669.1XP_047290625.1  PSME3-interacting protein isoform X2

    7. XM_047434677.1XP_047290633.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    8. XM_024450454.2XP_024306222.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    9. XM_047434672.1XP_047290628.1  PSME3-interacting protein isoform X2

    10. XM_047434671.1XP_047290627.1  PSME3-interacting protein isoform X2

    11. XM_047434675.1XP_047290631.1  PSME3-interacting protein isoform X2

    12. XM_047434670.1XP_047290626.1  PSME3-interacting protein isoform X2

    13. XM_047434673.1XP_047290629.1  PSME3-interacting protein isoform X2

    14. XM_017023704.1XP_016879193.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    15. XM_017023681.3XP_016879170.1  PSME3-interacting protein isoform X3

      Conserved Domains (1) summary
      pfam10187
      Location:21109
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    16. XM_047434668.1XP_047290624.1  PSME3-interacting protein isoform X1

    17. XM_017023703.2XP_016879192.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
      Conserved Domains (1) summary
      pfam10187
      Location:15116
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      62948740..62982387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054313972.1XP_054169947.1  PSME3-interacting protein isoform X2

    2. XM_054313982.1XP_054169957.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    3. XM_054313973.1XP_054169948.1  PSME3-interacting protein isoform X2

    4. XM_054313971.1XP_054169946.1  PSME3-interacting protein isoform X2

    5. XM_054313975.1XP_054169950.1  PSME3-interacting protein isoform X2

    6. XM_054313986.1XP_054169961.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    7. XM_054313985.1XP_054169960.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    8. XM_054313984.1XP_054169959.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    9. XM_054313980.1XP_054169955.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    10. XM_054313976.1XP_054169951.1  PSME3-interacting protein isoform X2

    11. XM_054313970.1XP_054169945.1  PSME3-interacting protein isoform X2

    12. XM_054313974.1XP_054169949.1  PSME3-interacting protein isoform X2

    13. XM_054313989.1XP_054169964.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    14. XM_054313981.1XP_054169956.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    15. XM_054313978.1XP_054169953.1  PSME3-interacting protein isoform X2

    16. XM_054313987.1XP_054169962.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    17. XM_054313983.1XP_054169958.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8
    18. XM_054313977.1XP_054169952.1  PSME3-interacting protein isoform X2

    19. XM_054313979.1XP_054169954.1  PSME3-interacting protein isoform X3

    20. XM_054313969.1XP_054169944.1  PSME3-interacting protein isoform X1

    21. XM_054313988.1XP_054169963.1  PSME3-interacting protein isoform X4

      UniProtKB/Swiss-Prot
      Q9GZU8