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    ATF2 activating transcription factor 2 [ Homo sapiens (human) ]

    Gene ID: 1386, updated on 9-Dec-2024

    Summary

    Official Symbol
    ATF2provided by HGNC
    Official Full Name
    activating transcription factor 2provided by HGNC
    Primary source
    HGNC:HGNC:784
    See related
    Ensembl:ENSG00000115966 MIM:123811; AllianceGenome:HGNC:784
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HB16; CREB2; TREB7; CREB-2; CRE-BP1
    Summary
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
    Expression
    Ubiquitous expression in thyroid (RPKM 19.6), brain (RPKM 14.7) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ATF2 in Genome Data Viewer
    Location:
    2q31.1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (175072259..175168203, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (175561049..175656993, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (175936987..176032931, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12132 Neighboring gene RNA, U6 small nuclear 1290, pseudogene Neighboring gene ribosomal protein L21 pseudogene 31 Neighboring gene MPRA-validated peak3937 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:175921111-175921658 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:175921659-175922204 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:175930185-175930417 Neighboring gene MPRA-validated peak3938 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:175972107-175973047 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12133 Neighboring gene microRNA 933 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16787 Neighboring gene ATP synthase membrane subunit c locus 3 Neighboring gene ribosomal protein S15a pseudogene 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env HIV-1 gp120 and p300 synergistically increase TGF-beta, ATF-2 and activating protein-1 (AP-1) expression leading to tubular cell apoptosis; in addition, HIV-1 gp120 treatment causes phosphorylation of Smad2 and downregulation of c-Jun PubMed
    Nef nef ATF2 mRNA is selectively retained in HIV-1 Nef-expressing cellular exosomes, and three miRNAs (miR-17, miR-92a, and miR-21) which target ATF2 mRNA are selectively secreted in exosomes from these cells PubMed
    nef Nef inhibits ASK1/p38MAPK-dependent Mycobacterium tuberculosis-induced TNF-alpha production by inhibiting binding of ATF2 to the TNF-alpha promoter PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: CHN1

    Clone Names

    • MGC111558

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IC
    Inferred by Curator
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables cAMP response element binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cAMP response element binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cAMP response element binding protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone H2B acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone H4 acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone acetyltransferase activity TAS
    Traceable Author Statement
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables leucine zipper domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables promoter-specific chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA damage response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in NK T cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in abducens nucleus development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in adipose tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in apoptotic process involved in development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in brainstem development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to anisomycin IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to leucine starvation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to virus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detection of cell density IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in facial nucleus development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in growth plate cartilage chondrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in growth plate cartilage chondrocyte proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hematopoietic progenitor cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hepatocyte apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hypoglossal nucleus development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intrinsic apoptotic signaling pathway in response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in liver development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic intra-S DNA damage checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in motor neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in neurofilament cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in outflow tract morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in p38MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-threonine phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cardiac muscle myoblast proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transforming growth factor beta2 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in response to organic cyclic compound IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to osmotic stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in vacuole organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in white fat cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of H4 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of RNA polymerase II transcription regulator complex EXP
    Inferred from Experiment
    more info
    PubMed 
    part_of RNA polymerase II transcription regulator complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus EXP
    Inferred from Experiment
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclic AMP-dependent transcription factor ATF-2
    Names
    cAMP response element-binding protein CRE-BP1
    cAMP responsive element binding protein 2, formerly
    cAMP-dependent transcription factor ATF-2
    cyclic AMP-responsive element-binding protein 2
    histone acetyltransferase ATF2
    NP_001243019.1
    NP_001243020.1
    NP_001243021.1
    NP_001243022.1
    NP_001243023.1
    NP_001871.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_047045.1 RefSeqGene

      Range
      5004..100948
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001256090.2NP_001243019.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      See identical proteins and their annotated locations for NP_001243019.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) contains an additional 5' non-coding exon compared to variant 1. Variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003041
      Consensus CDS
      CCDS2262.1
      UniProtKB/Swiss-Prot
      A1L3Z2, A4D7U4, A4D7U5, A4D7V1, D3DPE9, G8JLM5, P15336, Q13000, Q3B7B7, Q4ZFU9, Q53RY2, Q8TAR1, Q96JT8
      UniProtKB/TrEMBL
      B3KY57
      Related
      ENSP00000376327.1, ENST00000392544.5
      Conserved Domains (4) summary
      cd12192
      Location:65102
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      cd14687
      Location:354414
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:2749
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05109
      Location:90342
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    2. NM_001256091.2NP_001243020.1  cyclic AMP-dependent transcription factor ATF-2 isoform 2

      See identical proteins and their annotated locations for NP_001243020.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) contains an additional 5' non-coding exon, and lacks another exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003049
      Consensus CDS
      CCDS58738.1
      UniProtKB/TrEMBL
      B3KY57
      Related
      ENSP00000407911.3, ENST00000426833.7
      Conserved Domains (4) summary
      cd12192
      Location:4784
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      cd14687
      Location:336396
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:931
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26386
      Location:184312
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    3. NM_001256092.2NP_001243021.1  cyclic AMP-dependent transcription factor ATF-2 isoform 3

      See identical proteins and their annotated locations for NP_001243021.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an internal exon compared to variant 1. This results in translation initiation from another start site, and a shorter isoform (3) with a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      BC107698, BX648469, DA995464
      Consensus CDS
      CCDS58737.1
      UniProtKB/TrEMBL
      B3KY57
      Related
      ENSP00000340576.5, ENST00000345739.9
      Conserved Domains (3) summary
      cd12192
      Location:944
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      PRK14951
      Location:144272
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd14687
      Location:296356
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    4. NM_001256093.2NP_001243022.1  cyclic AMP-dependent transcription factor ATF-2 isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an internal exon, and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. This results in translation initiation from another start site, and a shorter isoform (4) with distinct N- and C- termini compared to isoform 1.
      Source sequence(s)
      BC107698, BX648469, DA995464, DQ003048
      UniProtKB/TrEMBL
      A4D7V5
      Conserved Domains (2) summary
      cd12192
      Location:944
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      cd14687
      Location:296356
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    5. NM_001256094.2NP_001243023.1  cyclic AMP-dependent transcription factor ATF-2 isoform 5

      See identical proteins and their annotated locations for NP_001243023.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks several exons from the 3' end, and has a different 3' UTR compared to variant 1. This results in an isoform (5) with a shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AC007435, BC026175, DA995464
      Consensus CDS
      CCDS58739.1
      UniProtKB/TrEMBL
      E9PEK8
      Related
      ENSP00000386526.1, ENST00000409833.5
      Conserved Domains (2) summary
      cd12192
      Location:65102
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      sd00019
      Location:2749
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. NM_001880.4NP_001871.2  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      See identical proteins and their annotated locations for NP_001871.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 2 encode the same isoform.
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464
      Consensus CDS
      CCDS2262.1
      UniProtKB/Swiss-Prot
      A1L3Z2, A4D7U4, A4D7U5, A4D7V1, D3DPE9, G8JLM5, P15336, Q13000, Q3B7B7, Q4ZFU9, Q53RY2, Q8TAR1, Q96JT8
      UniProtKB/TrEMBL
      B3KY57
      Related
      ENSP00000264110.2, ENST00000264110.7
      Conserved Domains (4) summary
      cd12192
      Location:65102
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      cd14687
      Location:354414
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:2749
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05109
      Location:90342
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    RNA

    1. NR_045768.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) contains two additional exons compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003043
    2. NR_045769.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) contains two additional exons, and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003036
    3. NR_045770.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) contains two additional exons, and lacks another exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BX648469, DA995464, DQ003044
    4. NR_045771.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) contains an additional exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003039
    5. NR_045772.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) contains two additional exons, and lacks another exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003040
    6. NR_045773.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) contains an additional exon, and lacks another exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BC130335, BX648469, DA995464, DQ003046
    7. NR_045774.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) lacks an internal exon compared to variant 1. It is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC107698, BX648469, DA995464, DQ003047
      Related
      ENST00000409437.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      175072259..175168203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      175561049..175656993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)