CRC1 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: CRC1
Primary source: SGD:S000005626
Locus tag: YOR100C
See related: AllianceGenome:SGD:S000005626; FungiDB:YOR100C; VEuPathDB:YOR100C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables carnitine:acyl carnitine antiporter activity. Involved in fatty acid metabolic process. Located in mitochondrial inner membrane. Used to study lipid metabolism disorder. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acyl carnitine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables carnitine:acyl carnitine antiporter activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in acyl carnitine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in carnitine transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in carnitine transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in fatty acid metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in mitochondrial transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrial envelope	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

NP_014743.1

Mitochondrial inner membrane carnitine transporter; required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation; human homolog SLC25A20 complements yeast null mutant

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The following sections contain reference sequences that belong to a specific genome build. Explain