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    ICS2 Ics2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852454, updated on 1-Aug-2024

    Summary

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    Gene symbol
    ICS2
    Gene description
    Ics2p
    Primary source
    FungiDB:YBR157C
    Locus tag
    YBR157C
    See related
    SGD:S000000361; AllianceGenome:SGD:S000000361; VEuPathDB:YBR157C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

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    See ICS2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (553543..554310, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene HSP70/90 family co-chaperone CNS1 Neighboring gene Sli15p Neighboring gene Amn1p Neighboring gene ketoreductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and functional analysis of a 7.2 kb DNA fragment containing four open reading frames located between RPB5 and CDC28 on the right arm of chromosome II. Rose M, et al. Yeast, 1995 Jul. PMID 7483850
    2. Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Kim HJ, et al. Nat Genet, 2014 Feb. PMID 24336168, Free PMC Article
    3. P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance. Loll-Krippleber R, et al. Nat Commun, 2017 Sep 15. PMID 28916784, Free PMC Article
    4. A protein interaction map of the mitotic spindle. Wong J, et al. Mol Biol Cell, 2007 Oct. PMID 17634282, Free PMC Article
    5. Complete DNA sequence of yeast chromosome II. Feldmann H, et al. EMBO J, 1994 Dec 15. PMID 7813418, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Ics2p
    NP_009715.4
    • hypothetical protein; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      553543..554310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178505.3 → NP_009715.4  TPA: Ics2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009715.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQF2, P38284, Q86ZT4
      UniProtKB/TrEMBL
      A6ZL99, B3LN02, B5VEB3, C7GUU7, N1PAU0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38284.2

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