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    GIP1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852334, updated on 11-Sep-2024

    Summary

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    Official Symbol
    GIP1
    Primary source
    SGD:S000000249
    Locus tag
    YBR045C
    See related
    AllianceGenome:SGD:S000000249; FungiDB:YBR045C; VEuPathDB:YBR045C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein phosphatase 1 binding activity and protein phosphatase regulator activity. Involved in ascospore wall assembly and regulation of phosphoprotein phosphatase activity. Located in prospore membrane. Part of protein phosphatase type 1 complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (328173..330092, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Tcm62p Neighboring gene tRNA-Val Neighboring gene NADPH:quinone reductase Neighboring gene Fmp23p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein phosphatase type 1-interacting protein Ysw1 is involved in proper septin organization and prospore membrane formation during sporulation. Ishihara M, et al. Eukaryot Cell, 2009 Jul. PMID 19465564, Free PMC Article
    2. A Gip1p-Glc7p phosphatase complex regulates septin organization and spore wall formation. Tachikawa H, et al. J Cell Biol, 2001 Nov 26. PMID 11724821, Free PMC Article
    3. Alternative modes of organellar segregation during sporulation in Saccharomyces cerevisiae. Suda Y, et al. Eukaryot Cell, 2007 Nov. PMID 17905927, Free PMC Article
    4. Arg-Pro-X-Ser/Thr is a consensus phosphoacceptor sequence for the meiosis-specific Ime2 protein kinase in Saccharomyces cerevisiae. Moore M, et al. Biochemistry, 2007 Jan 9. PMID 17198398, Free PMC Article
    5. Dynamic localization of a yeast development-specific PP1 complex during prospore membrane formation is dependent on multiple localization signals and complex formation. Nakamura TS, et al. Mol Biol Cell, 2017 Dec 15. PMID 29046399, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genetic analysis suggests that a Gip1-Glc7 phosphatase complex regulates prospore membrane extension in parallel to the previously reported Vps13, Spo71, Spo73 pathway.
      Title: Dynamic localization of a yeast development-specific PP1 complex during prospore membrane formation is dependent on multiple localization signals and complex formation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables protein phosphatase 1 binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein phosphatase regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein phosphatase type 1 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase regulator GIP1
    NP_009601.2
    • Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      328173..330092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178393.2 → NP_009601.2  TPA: protein phosphatase regulator GIP1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009601.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ45, P38229
      UniProtKB/TrEMBL
      G2W951, N1P9D2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38229.2

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