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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855487, updated on 18-Sep-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000005178
    Locus tag
    YNL234W
    See related
    AllianceGenome:SGD:S000005178; FungiDB:YNL234W; VEuPathDB:YNL234W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables heme binding activity. Predicted to be involved in cellular response to nitrosative stress and nitric oxide catabolic process. Located in fungal-type vacuole membrane. Orthologous to human NGB (neuroglobin). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (210233..211513)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Ytp1p Neighboring gene Sin4p Neighboring gene Bni4p Neighboring gene exosome non-catalytic core subunit CSL4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a new hemoprotein in the yeast Saccharomyces cerevisiae. Sartori G, et al. J Biol Chem, 1999 Feb 19. PMID 9988749
    2. Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest. Liu Y, et al. Mol Gen Genet, 2000 Jan. PMID 10660074
    3. The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open reading frames including a novel gene encoding a globin-like domain. Pandolfo D, et al. Yeast, 1996 Sep. PMID 8896273
    4. Regulatory network connecting two glucose signal transduction pathways in Saccharomyces cerevisiae. Kaniak A, et al. Eukaryot Cell, 2004 Feb. PMID 14871952, Free PMC Article
    5. Identification of aneuploidy-tolerating mutations. Torres EM, et al. Cell, 2010 Oct 1. PMID 20850176, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables FAD binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitric oxide dioxygenase NAD(P)H activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cellular response to nitrosative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nitric oxide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole membrane HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_014165.1
    • hypothetical protein with similarity to globins; has a functional heme-binding domain; mutant has aneuploidy tolerance; transcription induced by stress conditions; may be involved in glucose signaling or metabolism; regulated by Rgt1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      210233..211513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183072.1 → NP_014165.1  TPA: uncharacterized protein YNL234W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0V8, P53857
      UniProtKB/TrEMBL
      B3LP75, B5VQH5, C8ZG01
      Conserved Domains (1) summary
      cd01040
      Location:178 → 293
      Mb-like; myoglobin-like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53857.1

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