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    2210408I21Rik RIKEN cDNA 2210408I21 gene [ Mus musculus (house mouse) ]

    Gene ID: 72371, updated on 28-Oct-2024

    Summary

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    Official Symbol
    2210408I21Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2210408I21 geneprovided by MGI
    Primary source
    MGI:MGI:1919621
    See related
    Ensembl:ENSMUSG00000071252 AllianceGenome:MGI:1919621
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Is expressed in several structures, including adipose tissue; adrenal gland; genitourinary system; gut; and nervous system. Orthologous to human KIAA0825 (KIAA0825). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in testis adult (RPKM 2.4), CNS E18 (RPKM 0.9) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See 2210408I21Rik in Genome Data Viewer
    Location:
    13 C1; 13 40.98 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (77283636..77761904)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (77135531..77613785)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene multiple C2 domains, transmembrane 1 Neighboring gene chromatin modifying protein 2A pseudogene Neighboring gene 60S ribosomal protein L17-like Neighboring gene SMC5-SMC6 complex localization factor 1 Neighboring gene STARR-seq mESC enhancer starr_35066 Neighboring gene VISTA enhancer mm881 Neighboring gene STARR-seq mESC enhancer starr_35067 Neighboring gene STARR-seq mESC enhancer starr_35068 Neighboring gene STARR-seq mESC enhancer starr_35069 Neighboring gene STARR-seq mESC enhancer starr_35070 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1, pseudogene Neighboring gene predicted gene, 26088

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107105

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein KIAA0825 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081353.2 → NP_001074822.1  uncharacterized protein KIAA0825 homolog isoform 2

      See identical proteins and their annotated locations for NP_001074822.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an early polyA signal that omits 16 exons from the 3' end, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC122418
      Consensus CDS
      CCDS88493.1
      UniProtKB/TrEMBL
      Q3TNF8
      Related
      ENSMUSP00000153096.2, ENSMUST00000225605.2

    2. NM_001145676.2 → NP_001139148.1  uncharacterized protein KIAA0825 homolog isoform 1

      See identical proteins and their annotated locations for NP_001139148.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC099692, AC122418, AC141892, AC158511
      Consensus CDS
      CCDS49316.1
      UniProtKB/Swiss-Prot
      E9Q2V0, Q3TPR6, Q3UPC7, Q5FWD2, Q8BQF4, Q9D7T8
      UniProtKB/TrEMBL
      B9EKQ6
      Related
      ENSMUSP00000127449.2, ENSMUST00000168779.3
      Conserved Domains (1) summary
      pfam14906
      Location:515 → 832
      DUF4495; Domain of unknown function (DUF4495)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      77283636..77761904
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517397.5 → XP_006517460.1  uncharacterized protein KIAA0825 homolog isoform X4

      UniProtKB/TrEMBL
      B9EKQ6
      Conserved Domains (1) summary
      pfam14906
      Location:515 → 832
      DUF4495; Domain of unknown function (DUF4495)

    2. XM_036158179.1 → XP_036014072.1  uncharacterized protein KIAA0825 homolog isoform X1

      UniProtKB/TrEMBL
      B9EKQ6
      Conserved Domains (1) summary
      pfam14906
      Location:515 → 832
      DUF4495; Domain of unknown function (DUF4495)

    3. XM_036158180.1 → XP_036014073.1  uncharacterized protein KIAA0825 homolog isoform X2

      UniProtKB/TrEMBL
      B9EKQ6
      Conserved Domains (1) summary
      pfam14906
      Location:515 → 832
      DUF4495; Domain of unknown function (DUF4495)

    4. XM_036158181.1 → XP_036014074.1  uncharacterized protein KIAA0825 homolog isoform X3

      UniProtKB/TrEMBL
      B9EKQ6
      Conserved Domains (1) summary
      pfam14906
      Location:461 → 778
      DUF4495; Domain of unknown function (DUF4495)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_028215.1: Suppressed sequence

      Description
      NM_028215.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UPC7.3 GenPept UniProtKB/Swiss-Prot:Q3UPC7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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