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    copg2 COPI coat complex subunit gamma 2 [ Danio rerio (zebrafish) ]

    Gene ID: 30187, updated on 2-Nov-2024

    Summary

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    Official Symbol
    copg2provided by ZNC
    Official Full Name
    COPI coat complex subunit gamma 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000208-8
    See related
    Ensembl:ENSDARG00000034823 AllianceGenome:ZFIN:ZDB-GENE-000208-8
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    copg; cb943; fi31b06; wu:fi31b06
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport; organelle transport along microtubule; and protein secretion. Predicted to act upstream of or within intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of COPI vesicle coat. Predicted to be active in Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including axis; notochord; periderm; polster; and solid lens vesicle. Orthologous to human COPG2 (COPI coat complex subunit gamma 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See copg2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (15983609..15996191)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (15984854..15997436)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene si:dkey-117n7.5 Neighboring gene urocortin 3, like Neighboring gene mesoderm specific transcript Neighboring gene uncharacterized LOC110439358 Neighboring gene uncharacterized LOC101884691

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structure and expression of the zebrafish mest gene, an ortholog of mammalian imprinted gene PEG1/MEST. Hahn Y, et al. Biochim Biophys Acta, 2005 Nov 10. PMID 16263186
    2. Impairment of Cargo Transportation Caused by gbf1 Mutation Disrupts Vascular Integrity and Causes Hemorrhage in Zebrafish Embryos. Chen J, et al. J Biol Chem, 2017 Feb 10. PMID 28003365, Free PMC Article
    3. Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Beaudoin JD, et al. Nat Struct Mol Biol, 2018 Aug. PMID 30061596, Free PMC Article
    4. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Newman M, et al. Mol Brain, 2019 May 3. PMID 31053140, Free PMC Article
    5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organelle transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of COPI vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coatomer subunit gamma-2
    Names
    coatomer protein complex, subunit gamma 2
    gamma-2-COP
    gamma-2-coat protein
    gamma-cop
    gamma2-cop

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130994.1 → NP_571069.1  coatomer subunit gamma-2

      See identical proteins and their annotated locations for NP_571069.1

      Status: PROVISIONAL

      Source sequence(s)
      AF191561
      UniProtKB/Swiss-Prot
      Q1L8N9, Q4V9K1, Q7ZVC5, Q9PUE3, Q9PUE4
      Related
      ENSDARP00000043659.7, ENSDART00000043660.8
      Conserved Domains (5) summary
      COG5240
      Location:7 → 868
      SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
      pfam08752
      Location:615 → 758
      COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
      pfam11701
      Location:325 → 497
      UNC45-central; Myosin-binding striated muscle assembly central
      pfam16381
      Location:760 → 872
      Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
      sd00044
      Location:398 → 423
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      15983609..15996191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9PUE4.2 GenPept UniProtKB/Swiss-Prot:Q9PUE4

    Gene LinkOut

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