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    inavab innate immunity activator b [ Danio rerio (zebrafish) ]

    Gene ID: 563192, updated on 2-Nov-2024

    Summary

    Official Symbol
    inavabprovided by ZNC
    Official Full Name
    innate immunity activator bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-190
    See related
    Ensembl:ENSDARG00000070571 AllianceGenome:ZFIN:ZDB-GENE-061103-190
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fk70d05; zgc:153953
    Summary
    Predicted to be involved in adherens junction maintenance and positive regulation of protein ubiquitination. Human ortholog(s) of this gene implicated in inflammatory bowel disease 29. Orthologous to human INAVA (innate immunity activator). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See inavab in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24716790..24756816)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24478945..24519200)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886928 Neighboring gene G protein-coupled receptor 25 Neighboring gene arginyl aminopeptidase (aminopeptidase B) Neighboring gene cytochrome b5 reductase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    innate immunity activator b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080005.1NP_001073474.1  innate immunity activator b

      See identical proteins and their annotated locations for NP_001073474.1

      Status: PROVISIONAL

      Source sequence(s)
      BC125922
      UniProtKB/TrEMBL
      A0A8N1YZP0, A0JML5
      Related
      ENSDARP00000082173.5, ENSDART00000087740.6
      Conserved Domains (1) summary
      pfam11819
      Location:8136
      DUF3338; Domain of unknown function (DUF3338)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      24716790..24756816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169303.5XP_005169360.1  innate immunity activator b isoform X1

      See identical proteins and their annotated locations for XP_005169360.1

      UniProtKB/TrEMBL
      A0A8N1YZP0, A0JML5
      Conserved Domains (1) summary
      pfam11819
      Location:8136
      DUF3338; Domain of unknown function (DUF3338)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394820.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      222991..251898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)