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    lipt2 lipoyl(octanoyl) transferase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 664765, updated on 2-Nov-2024

    Summary

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    Official Symbol
    lipt2provided by ZNC
    Official Full Name
    lipoyl(octanoyl) transferase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060312-18
    See related
    Ensembl:ENSDARG00000069852 AllianceGenome:ZFIN:ZDB-GENE-060312-18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:136925
    Summary
    Predicted to enable lipoyl(octanoyl) transferase activity. Predicted to be involved in positive regulation of oxygen metabolic process and protein lipoylation. Predicted to act upstream of or within protein modification process. Predicted to be active in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See lipt2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (4957780..4969258, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (4966633..4978060, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:dkey-35i13.1 Neighboring gene uncharacterized LOC137487715 Neighboring gene ring finger protein 169 Neighboring gene signal peptidase complex subunit 2 Neighboring gene defensin, beta-like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC136925

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipoyl(octanoyl) transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipoyl(octanoyl) transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipoyl(octanoyl) transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of oxygen metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within protein lipoylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein lipoylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within protein modification process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
    Names
    lipoate-protein ligase B
    lipoyl(octanoyl) transferase 2 (putative)
    lipoyl/octanoyl transferase
    lipoyltransferase 2
    octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
    octanoyltransferase-like
    putative lipoyltransferase 2, mitochondrial
    putative octanoyltransferase, mitochondrial
    NP_001035082.1
    XP_005157452.1
    XP_005157453.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039993.1 → NP_001035082.1  octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001035082.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114309
      UniProtKB/Swiss-Prot
      Q29R99
      Related
      ENSDARP00000092768.1, ENSDART00000101992.2
      Conserved Domains (1) summary
      cl14057
      Location:13 → 220
      BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      4957780..4969258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157396.4 → XP_005157453.1  octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005157453.1

      UniProtKB/TrEMBL
      A0A8M2B3H2, F1QAW5
      Conserved Domains (1) summary
      cl14057
      Location:13 → 220
      BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family

    2. XM_005157395.5 → XP_005157452.1  octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005157452.1

      UniProtKB/TrEMBL
      A0A8M2B3H2, F1QAW5
      Related
      ENSDARP00000155831.1, ENSDART00000180551.1
      Conserved Domains (1) summary
      cl14057
      Location:13 → 220
      BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29R99.1 GenPept UniProtKB/Swiss-Prot:Q29R99

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