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    tcf25 transcription factor 25 (basic helix-loop-helix) [ Danio rerio (zebrafish) ]

    Gene ID: 445817, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tcf25provided by ZNC
    Official Full Name
    transcription factor 25 (basic helix-loop-helix)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040905-2
    See related
    Ensembl:ENSDARG00000040861 AllianceGenome:ZFIN:ZDB-GENE-040905-2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101131
    Summary
    Predicted to be located in cytoplasm. Predicted to be part of RQC complex. Is expressed in lens; mesoderm; notochord; and somite. Orthologous to human TCF25 (transcription factor 25). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tcf25 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (31117274..31206836)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (31138892..31228504)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene cytochrome b-245, alpha polypeptide Neighboring gene programmed cell death 5 Neighboring gene melanocortin 1 receptor Neighboring gene differentially expressed in FDCP 8 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization and expression pattern of ZB and PS transposons in zebrafish. Wang Y, et al. Gene Expr Patterns, 2021 Dec. PMID 34481069
    2. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC101131

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    part_of RQC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosome quality control complex subunit TCF25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005399.1 → NP_001005399.1  ribosome quality control complex subunit TCF25

      See identical proteins and their annotated locations for NP_001005399.1

      Status: PROVISIONAL

      Source sequence(s)
      BC080235
      UniProtKB/TrEMBL
      Q68EJ4
      Related
      ENSDARP00000059892.7, ENSDART00000059893.7
      Conserved Domains (1) summary
      pfam04910
      Location:217 → 562
      Tcf25; Transcriptional repressor TCF25

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      31117274..31206836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159180.5 → XP_005159237.1  ribosome quality control complex subunit TCF25 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B5S3
      Related
      ENSDARP00000119333.3, ENSDART00000138403.4
      Conserved Domains (1) summary
      pfam04910
      Location:217 → 557
      Tcf25; Transcriptional repressor TCF25

    2. XM_068214759.1 → XP_068070860.1  ribosome quality control complex subunit TCF25 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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