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    surf6 surfeit 6 [ Danio rerio (zebrafish) ]

    Gene ID: 394040, updated on 9-Dec-2024

    Summary

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    Official Symbol
    surf6provided by ZNC
    Official Full Name
    surfeit 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1333
    See related
    Ensembl:ENSDARG00000035427 AllianceGenome:ZFIN:ZDB-GENE-040426-1333
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    surf6l; zgc:64008
    Summary
    Acts upstream of or within heart development. Predicted to be located in nucleus. Is expressed in several structures, including alar plate midbrain region; immature eye; midbrain; retina; and segmental plate. Orthologous to human SURF6 (surfeit 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See surf6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33275151..33281122, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32675000..32680928, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene interferon induced transmembrane protein 1 Neighboring gene kynurenine aminotransferase 1 Neighboring gene SURF1 cytochrome c oxidase assembly factor Neighboring gene small nucleolar RNA SNORD36 Neighboring gene ribosomal protein L7a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Milan DJ, et al. Circulation, 2009 Aug 18. PMID 19652097, Free PMC Article
    2. Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development. Hensley MR, et al. Sci Rep, 2016 Jun 13. PMID 27292017, Free PMC Article
    3. ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. Krens SF, et al. BMC Genomics, 2008 Apr 28. PMID 18442396, Free PMC Article
    4. Positive correlation between gene coexpression and positional clustering in the zebrafish genome. Ng YK, et al. BMC Genomics, 2009 Jan 22. PMID 19159490, Free PMC Article
    5. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC64008

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    surfeit locus protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201065.1 → NP_957359.1  surfeit locus protein 6

      See identical proteins and their annotated locations for NP_957359.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053193
      UniProtKB/TrEMBL
      Q7T3A6
      Related
      ENSDARP00000051343.5, ENSDART00000051344.6
      Conserved Domains (1) summary
      pfam04935
      Location:194 → 350
      SURF6; Surfeit locus protein 6

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      33275151..33281122 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171804.5 → XP_005171861.1  surfeit locus protein 6 isoform X1

      See identical proteins and their annotated locations for XP_005171861.1

      UniProtKB/TrEMBL
      A0A8M2BJL3, Q6DRK9
      Related
      ENSDARP00000121048.1, ENSDART00000138116.3
      Conserved Domains (1) summary
      pfam04935
      Location:194 → 350
      SURF6; Surfeit locus protein 6
    Nucleotide Protein Strain
    Heading Accession and Version

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