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    tuba8l3 tubulin, alpha 8 like 3 [ Danio rerio (zebrafish) ]

    Gene ID: 445164, updated on 9-Dec-2024

    Summary

    Official Symbol
    tuba8l3provided by ZNC
    Official Full Name
    tubulin, alpha 8 like 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-77
    See related
    Ensembl:ENSDARG00000070155 AllianceGenome:ZFIN:ZDB-GENE-040801-77
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tuba8l3a; zgc:101117
    Summary
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within glial cell development and myelination. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in brain; cranial ganglion; periventricular grey zone; and retinal inner nuclear layer. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tuba8l3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (7662642..7673856, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (7684251..7695465, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type Na Neighboring gene microRNA 153c Neighboring gene DnaJ heat shock protein family (Hsp40) member B2 Neighboring gene uncharacterized LOC137496446 Neighboring gene uncharacterized LOC137496447 Neighboring gene tubulin, alpha 8 like 5 Neighboring gene motor neuron and pancreas homeobox 2a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within glial cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within myelination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tubulin, alpha 8 like 3
    Names
    pma
    puma
    tubulin alpha 8-like 3a protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003558.2NP_001003558.1  tubulin, alpha 8 like 3

      See identical proteins and their annotated locations for NP_001003558.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078237
      UniProtKB/TrEMBL
      A0A8M9Q636, A8E5F9, F6P853, Q6DC49
      Related
      ENSDARP00000093490.4, ENSDART00000102715.5
      Conserved Domains (2) summary
      PTZ00335
      Location:1439
      PTZ00335; tubulin alpha chain; Provisional
      cd02186
      Location:2435
      alpha_tubulin; The alpha-tubulin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      7662642..7673856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)