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    vtg4 vitellogenin 4 [ Danio rerio (zebrafish) ]

    Gene ID: 678536, updated on 14-Nov-2024

    Summary

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    Official Symbol
    vtg4provided by ZNC
    Official Full Name
    vitellogenin 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-001201-3
    See related
    Ensembl:ENSDARG00000078429 AllianceGenome:ZFIN:ZDB-GENE-001201-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb59b02; wu:fb59d07; wu:fb59e10; zgc:136286; zgc:136383; si:rp71-23d18.3
    Summary
    Predicted to enable lipid transporter activity. Predicted to be involved in cellular response to estrogen stimulus and response to estradiol. Predicted to act upstream of or within lipid transport. Part of protein-containing complex. Is expressed in female organism; intestine; and liver. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See vtg4 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (24784016..24791505, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (24756392..24763881, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene vitellogenin 5 Neighboring gene si:rp71-23d18.4 Neighboring gene vitellogenin-like Neighboring gene vitellogenin 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A zebrafish vitellogenin gene (vg3) encodes a novel vitellogenin without a phosvitin domain and may represent a primitive vertebrate vitellogenin gene. Wang H, et al. Gene, 2000 Oct 3. PMID 11054560
    2. One-dimensional proteomic profiling of Danio rerio embryo vitellogenin to estimate quantum dot toxicity. Petushkova NA, et al. Proteome Sci, 2015. PMID 25964724, Free PMC Article
    3. Temporal dynamics of oocyte growth and vitellogenin gene expression in zebrafish (Danio rerio). Connolly MH, et al. Zebrafish, 2014 Apr. PMID 24611554
    4. Affinity isolation and mass spectral analysis of 1,10-phenanthroline (OP)-stimulated UV-damaged-DNA binding proteins expressed in zebrafish (Danio rerio) embryos. Lai YS, et al. Fish Physiol Biochem, 2012 Aug. PMID 22252336
    5. No bioavailability of 17α-ethinylestradiol when associated with nC60 aggregates during dietary exposure in adult male zebrafish (Danio rerio). Park JW, et al. Chemosphere, 2010 Nov. PMID 20937515

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC136286, MGC136383

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nutrient reservoir activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vitellogenin 4
    Names
    vg4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045294.2 → NP_001038759.2  vitellogenin 4 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AW019833, BC115069, BF718166, DY546145, DY556094, EB874546, EB876279, EB878699
      UniProtKB/TrEMBL
      A0A8M1NAN4
      Related
      ENSDARP00000115012.1, ENSDART00000136837.2
      Conserved Domains (3) summary
      pfam01347
      Location:24 → 592
      Vitellogenin_N; Lipoprotein amino terminal region
      pfam09172
      Location:626 → 917
      DUF1943; Domain of unknown function (DUF1943)
      pfam09175
      Location:1166 → 1330
      DUF1944; Domain of unknown function (DUF1944)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      24784016..24791505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395108.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      120365..127854 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001040295.1: Suppressed sequence

      Description
      NM_001040295.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein
    Heading Accession and Version

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