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    tuba2 tubulin, alpha 2 [ Danio rerio (zebrafish) ]

    Gene ID: 406303, updated on 2-Nov-2024

    Summary

    Official Symbol
    tuba2provided by ZNC
    Official Full Name
    tubulin, alpha 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1970
    See related
    Ensembl:ENSDARG00000045014 AllianceGenome:ZFIN:ZDB-GENE-040426-1970
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73108
    Summary
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in lens. Orthologous to human TUBA4B (tubulin alpha 4b). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tuba2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (3336524..3343463, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (3268364..3275303, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene SAP domain containing ribonucleoprotein Neighboring gene peripherin Neighboring gene sulfite oxidase Neighboring gene microspherule protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213030.1NP_998195.1  tubulin, alpha 2

      See identical proteins and their annotated locations for NP_998195.1

      Status: PROVISIONAL

      Source sequence(s)
      BC060904
      UniProtKB/TrEMBL
      A0A8M1PEG3, Q6P972
      Related
      ENSDARP00000066176.4, ENSDART00000066177.6
      Conserved Domains (2) summary
      PTZ00335
      Location:1440
      PTZ00335; tubulin alpha chain; Provisional
      cd02186
      Location:2435
      alpha_tubulin; The alpha-tubulin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      3336524..3343463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)